Covalent Insertion of Antioxidant Molecules on Chitosan by a Free Radical Grafting Procedure
Covalent Insertion of Antioxidant Molecules on Chitosan by a Free Radical Grafting Procedure
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DOI：
10.1021/jf900778u
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发表时间：
2009-07-08
影响因子：
6.1
通讯作者：
Picci, Nevio
中科院分区：
文献类型：
--
作者：
Curcio, Manuela;Puoci, Francesco;Picci, Nevio
本工作采用自由基接枝法合成了没食子酸-壳聚糖和儿茶素-壳聚糖偶联物。为此，使用抗坏血酸/过氧化氢氧化还原对作为自由基引发剂。通过UV、FT-IR和DSC分析证实了抗氧剂与生物聚合物之间形成了共价键，而壳聚糖偶联物的抗氧化性能与空白壳聚糖在相同条件下处理但没有抗氧化剂分子的情况下进行了比较。功能化材料表现出良好的抗氧化活性，证明了该反应方法的有效性。
In this work, the synthesis of gallic acid-chitosan and catechin-chitosan conjugates was carried out by adopting a free radical-induced grafting procedure. For this purpose, an ascorbic acid/hydrogen peroxide redox pair was employed as radical initiator. The formation of covalent bonds between antioxidant and biopolymer was verified by performing UV, FT-IR, and DSC analyses, whereas the antioxidant properties of chitosan conjugates were compared with that of a blank chitosan, treated in the same conditions but in the absence of antioxidant molecules. The good antioxidant activity shown by functionalized materials proved the efficiency of the reaction method.