An efficient and reusable ionic liquid catalyst for the synthesis of 14-aryl-14H-dibenzo[a,j]xanthenes under solvent-free conditions
An efficient and reusable ionic liquid catalyst for the synthesis of 14-aryl-14H-dibenzo[a,j]xanthenes under solvent-free conditions
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一种高效、可重复使用的离子液体催化剂，用于无溶剂条件下合成 14-芳基-14H-二苯并[a,j]呫吨
DOI：
10.1039/c4ra06521b
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发表时间：
2014
期刊：
影响因子：
3.9
通讯作者：
Wang Jianji
中科院分区：
文献类型：
--
作者：
Zhu Anlian;Bai Shukun;Jin Wei;Liu Ruixia;Li Lingjun;Zhao Yang;Wang Jianji
在本工作中，发现酸性质子离子液体N，N-二甲氨基乙醇硫酸氢盐（[DMEA][HSO 4]）是一种有效的、可重复使用的催化剂，可用于在无溶剂条件下一锅法合成14-芳基-14H-二苯并[a，j]氧杂蒽。这种离子液体非常便宜，对空气和水稳定，并且可以容易地回收和重复使用至少六个循环。本文所述的催化体系是一种绿色方案，因为在一锅法合成14-芳基-14 H-二苯并[a，j]氧杂蒽中，目标化合物的产率优异，操作和后处理程序简单，并且没有使用挥发性有机溶剂。研究表明，该离子液体的阳离子和阴离子协同作用是其高催化活性和高化学选择性的主要原因。放大实验也表明该催化体系具有工业应用潜力。
In this work, it was found that acidic protic ionic liquid N,N-dimethylaminoethanol hydrosulfate ([DMEA][HSO4]) was an efficient and reusable catalyst for the one-pot synthesis of 14-aryl-14H-dibenzo[a,j]xanthenes under solvent-free conditions. This ionic liquid is very cheap, air and water stable, and can be easily recovered and reused for at least six cycles. The catalytic system described here is a green protocol since in the one-pot synthesis of 14-aryl-14H-dibenzo[a,j]xanthenes, the yield of the target compounds is excellent, operation and work-up procedures are simple, and no volatile organic solvents have been used. It is suggested that the synergetic effect of the cation and the anion of this ionic liquid is the main reason for the high catalytic activity and high chemo-selectivity. Scale-up experiments also suggest that this catalytic system has potential in industrial application.