TUMOR-METASTASIS FORMATION - CELL-SURFACE PROTEINS CONFER METASTASIS-PROMOTING OR METASTASIS-SUPPRESSING PROPERTIES
TUMOR-METASTASIS FORMATION - CELL-SURFACE PROTEINS CONFER METASTASIS-PROMOTING OR METASTASIS-SUPPRESSING PROPERTIES
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DOI：
10.1016/0304-419x(94)90002-7
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发表时间：
1994-05-27
影响因子：
11.2
通讯作者：
HERRLICH, P
中科院分区：
文献类型：
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作者：
PONTA, H;SLEEMAN, J;HERRLICH, P
癌症患者死于远处转移，这一事实充分证明了一个事实，即原发肿瘤已通过手术切除的患者的5年生存数据很差。早期切除提高了存活率，这表明在早期阶段，肿瘤细胞要么还没有机会或数量扩散，要么还没有形成转移形成所需的特性。是什么让肿瘤转移-
Cancer patients die of distant metastases, a fact amply documented by the poor 5-year survival data of patients whose primary tumor has been surgically removed. Early removal enhances the chance of survival, suggesting that there are early stages when tumor cells have either not yet had the opportunity or number to spread, or have not developed the properties needed for metastasis formation. What makes tumors metasta-