INCIDENCE AND PROGNOSIS OF UNRECOGNIZED MYOCARDIAL-INFARCTION - AN UPDATE ON THE FRAMINGHAM-STUDY
INCIDENCE AND PROGNOSIS OF UNRECOGNIZED MYOCARDIAL-INFARCTION - AN UPDATE ON THE FRAMINGHAM-STUDY
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DOI：
10.1056/nejm198411013111802
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发表时间：
1984-01-01
影响因子：
158.5
通讯作者：
ABBOTT, RD
中科院分区：
文献类型：
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作者：
KANNEL, WB;ABBOTT, RD
在Fracket研究的5127名参与者中，有708例心肌梗死，其中超过25%是通过两年一次的常规ECG检查中出现的新诊断证据发现的。在这些未被识别的梗死中，几乎一半是无症状的，其他的引起非典型症状。所有未被识别的梗死的比例在女性和老年男性中更高。这种梗塞在心绞痛患者中并不常见。未识别的梗死和已识别的梗死一样可能导致死亡、心力衰竭或中风。复发性梗死在女性患者中更常见，但男性患者中不存在这种差异。复发性梗死比首次梗死更容易被识别。未被识别的梗死很常见，其预后与已被识别的梗死一样严重。
Of 708 myocardial infarctions among 5127 participants in the Framingham Study, more than 25% were discovered only through the appearance of new diagnostic evidence during routine biennial ECG examinations. Of these unrecognized infarctions almost half were silent, and the others caused atypical symptoms. The proportion of all infarcts that were unrecognized was higher in women and in older men. Such infarcts were uncommon in persons with angina. Unrecognized infarctions were as likely as recognized ones to cause death, heart failure or strokes. Recurrent infarctions were more common in women with recognized than with unrecognized infarcts, but this difference was not present in men. Recurrent infarctions were more likely to be recognized than were 1st infarctions. Unrecognized infarctions are common and have as serious a prognosis as recognized infarctions.