A stable backbone for the fungi
A stable backbone for the fungi
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真菌的稳定骨架
DOI：
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
A. Haeseler
中科院分区：
文献类型：
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作者：
I. Ebersberger;M. Gube;Sascha Strauss;A. Kupczok;Martin Eckart;K. Voigt;E. Kothe;A. Haeseler
真菌在生物圈中很丰富。就有文字记载的历史而言，它们令人类着迷，并对我们的文化产生了相当大的影响。在生物技术、细胞生物学、遗传学和生命科学中，一般真菌构成相关的模式生物。一旦真菌的系统发育关系得到稳定的解决，真菌研究的个别结果就可以结合成一个整体的生物学图景。然而，尽管最近取得了进展，但真菌致病性的支柱尚未完全解决。特别是真菌的早期进化历史和子囊菌纲内的目或下位关系仍然不确定。在这里，我们提出了第一个真菌基因组研究的真核生物王国，合并所有公开可用的真菌基因组和表达序列标签（EST），建立一个数据集，包括128个基因和146个类群。由此产生的树提供了一个稳定的真菌系统发育的骨干。此外，我们提出了第一个正式的超树的基础上161真菌类群和128基因树。来自树木的综合证据支持真菌群的深层稳定性，以实现真菌的综合自然系统。他们指出，真菌的分类，特别是它们与微孢子虫的联盟，需要仔细修订。我们的分析也是一个库存的现今序列信息的真菌。它提供了从当前数据中可以得出哪些遗传学结论以及哪些不能得出的见解，并可作为指导进一步测序计划的指南。再加上全面的动物胚胎发生学，我们提供了三个支柱中的第二个，以了解多细胞真核生物界，真菌，后生动物和植物在过去16亿年的进化。
Fungi are abundant in the biosphere. They have fascinated mankind as far as written history goes and have considerably influenced our culture. In biotechnology, cell biology, genetics, and life sciences in general fungi constitute relevant model organisms. Once the phylogenetic relationships of fungi are stably resolved individual results from fungal research can be combined into a holistic picture of biology. However, and despite recent progress, the backbone of the fungal phylogeny is not yet fully resolved. Especially the early evolutionary history of fungi and the order or below-order relationships within the ascomycetes remain uncertain. Here we present the first phylogenomic study for a eukaryotic kingdom that merges all publicly available fungal genomes and expressed sequence tags (EST) to build a data set comprising 128 genes and 146 taxa. The resulting tree provides a stable phylogenetic backbone for the fungi. Moreover, we present the first formal supertree based on 161 fungal taxa and 128 gene trees. The combined evidences from the trees support the deep-level stability of the fungal groups towards a comprehensive natural system of the fungi. They indicate that the classification of the fungi, especially their alliance with the Microsporidia, requires careful revision. Our analysis is also an inventory of present day sequence information for the fungi. It provides insights into which phylogenenetic conclusions can and which cannot be drawn from the current data and may serve as a guide to direct further sequencing initiatives. Together with a comprehensive animal phylogeny, we provide the second of three pillars to understand the evolution of the multicellular eukaryotic kingdoms, fungi, metazoa, and plants, in the past 1.6 billion years.
影响因子：
10.7
作者：
Keeling, PJ;Luker, MA;Palmer, JD
通讯作者：
Palmer, JD
影响因子：
10.7
作者：
Philippe, H;Lartillot, N;Brinkmann, H
通讯作者：
Brinkmann, H