Optimization of nanoparticle core size for magnetic particle imaging.
Optimization of nanoparticle core size for magnetic particle imaging.
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DOI:
10.1016/j.jmmm.2009.02.083
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发表时间:
2009
影响因子:
2.7
通讯作者:
Krishnan KM
中科院分区:
文献类型:
--
作者:
Ferguson RM;Minard KR;Krishnan KM
Magnetic particle imaging (MPI) is a powerful new research and diagnostic imaging platform that is designed to image the amount and location of superparamagnetic nanoparticles in biological tissue. Here, we present mathematical modeling results that show how MPI sensitivity and spatial resolution both depend on the size of the nanoparticle core and its other physical properties, and how imaging performance can be effectively optimized through rational core design. Modeling is performed using the properties of magnetite cores, since these are readily produced with a controllable size that facilitates quantitative imaging. Results show that very low detection thresholds (of a few nanograms Fe3O4) and sub-millimeter spatial resolution are possible with MPI.
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DOI:
10.1002/cmr.1008
发表时间:
2001-01-01
期刊:
CONCEPTS IN MAGNETIC RESONANCE
影响因子:
--
作者:
Minard, KR;Wind, RA
通讯作者:
Wind, RA
影响因子:
2.7
作者:
Rosensweig, RE
通讯作者:
Rosensweig, RE
影响因子:
3.5
作者:
Gleich, B.;Weizenecker, J.;Borgert, J.
通讯作者:
Borgert, J.
影响因子:
64.8
作者:
Gleich, B;Weizenecker, R
通讯作者:
Weizenecker, R
影响因子:
2.1
作者:
CHANTRELL, RW;POPPLEWELL, J;CHARLES, SW
通讯作者:
CHARLES, SW