Variability in B-mode ultrasound measurements in the Atherosclerosis Risk in Communities (ARIC) study
Variability in B-mode ultrasound measurements in the Atherosclerosis Risk in Communities (ARIC) study
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DOI：
10.1016/0301-5629(96)00039-7
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发表时间：
1996-01-01
影响因子：
2.9
通讯作者：
Heiss, G
中科院分区：
文献类型：
--
作者：
Chambless, LE;Zhong, MM;Heiss, G
社区动脉粥样硬化风险（ARIC）研究是一项多中心、长期流行病学研究，主要使用B型超声测量颈动脉内膜-中层壁厚度。为了评估B模式技术在人群研究中应用的测量过程的可靠性，来自四个中心的36名志愿者在三次访问中进行了扫描，间隔7-14天。给出了人与人之间、超声医师之间、超声医师内、阅片者之间和阅片者内变化的动脉壁厚度B模式测量值的变化分量的估计值，沿着给出了不同超声医师重复就诊时测量值之间的相关性R的估计值以及不同阅片者的读数。颈动脉分叉、颈内动脉、颈总动脉和三段总颈动脉平均内膜中层厚度的R估计值分别为0.69、0.60、0.54和0.66。当调整这些参数以解释辅助研究和主要ARIC研究之间的人间方差差异时，对于颈动脉分叉处和颈内动脉和颈总动脉处的平均颈动脉远壁内膜-中层厚度，适合ARIC研究人群的估计部位特异性可靠性系数分别为0.77、0.73和0.70。
The Atherosclerosis Risk in Communities (ARIC) study is a multicenter, long-term epidemiologic study that uses B-mode ultrasound primarily to measure carotid arterial intima-media wall thickness. To assess the reliability of the measurement process of this application of B-mode technology to population-based research, 36 volunteers from four centers were scanned at three visits, 7-14 days apart. Estimates of the components of variation in the B-mode measurements of artery wall thickness from between-person, between-sonographer, within-sonographer, between-reader and within-reader variation are presented, along with estimates of the correlation R between measures made at repeat visits by different sonographers and read by different readers. The estimates of R for mean intima-media thickness are 0.69, 0.60, 0.54 and 0.66 for the carotid bifurcation, internal carotid, common carotid, and three-segment overall carotid mean, respectively. When these are adjusted to account for differences in between-person variance between the ancillary study and the main ARIC study, the estimated site-specific reliability coefficients appropriate to the ARIC study population are 0.77, 0.73 and 0.70 for mean carotid far-wall intima-media thickness at the carotid bifurcation and the internal and common carotid arteries.