Asymmetric Iterative Hydration of Polyene Strategy to Cryptocaryols A and B

Asymmetric Iterative Hydration of Polyene Strategy to Cryptocaryols A and B
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多烯策略对隐香醇 A 和 B 的不对称迭代水合

DOI：
10.1055/s-0035-1561607
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发表时间：
2016
期刊：
Synthesis
影响因子：
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通讯作者：
O’Doherty, George
O’Doherty, George
中科院分区：
--
文献类型：
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作者：
Hunter, Thomas;Wang, Yanping;Zheng, Jiamin;O’Doherty, George

文献摘要

相似文献

介绍了两种迭代不对称水合方法合成全顺式和顺式/反式/顺式-1，3，5，7-四醇基序。这些假对称产物是1，3-己醇产物的合成前体。该路线的实用性的allsyn-1，3，5，7-四醇非对映异构体证明其在合成隐caryol A和B，以及立体异构体的使用。
The development of two iterative asymmetric hydration approaches to the synthesis of allsyn- andsyn/anti/syn-1,3,5,7-tetraol motifs is described. These pseudo-symmetric products are synthetic precursors for 1,3-hexol products. The utility of the route to the allsyn-1,3,5,7-tetraol diastereoisomer was demonstrated with its use in the synthesis of cryptocaryols A and B, as well as, stereoisomers.