Cloning, mapping and expression analysis of VPS33B, the human orthologue of rat Vbs33b
Cloning, mapping and expression analysis of VPS33B, the human orthologue of rat Vbs33b
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DOI：
10.1159/000015571
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发表时间：
2000-01-01
期刊：
影响因子：
--
通讯作者：
Escarceller, M
中科院分区：
文献类型：
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作者：
Carim, L;Sumoy, L;Escarceller, M
我们已经鉴定了大鼠Vps 33 b的人类直系同源物VPS 33 B。VPS 33 B基因编码2482个核苷酸，开放阅读框（ORF）为617个氨基酸，蛋白质分子量为70.6 kDa。VPS 33 B含有与参与蛋白质分选和囊泡运输的蛋白质家族共享的Sec-1结构域。VPS 33 B在睾丸组织中呈高表达。通过辐射杂交定位，将VPS 33 B定位于染色体15q26.1。版权所有（C）2000S.KargerAG，Basel.
We have identified VPS33B, the human ortholog of rat Vps33b. VPS33B encodes a transcript of 2482 nt with an ORF of 617 amino acids and a predicted protein size of 70.6 kDa. VPS33B contains a Sec-1 domain shared with a family of proteins involved in protein sorting and vesicular trafficking. Enriched expression of VPS33B was observed in testis. VPS33B was positioned at chromosome 15q26.1 by radiation hybrid mapping. Copyright(C)2000S.KargerAG,Basel.