A chemoselective route to β-enamino esters and thioesters.
A chemoselective route to β-enamino esters and thioesters.
复制标题
DOI：
10.1021/ol5005643
复制
发表时间：
2014-04-18
期刊：
影响因子：
5.2
通讯作者：
Burgess, Kevin
中科院分区：
文献类型：
--
作者：
Xin, Dongyue;Burgess, Kevin
研究了β-烯氨基酯、硫酯和酰胺的合成条件。这些反应涉及缓冲介质中的羟基苯并三唑衍生物。举例说明了一些杂环系统的合成，包括一些与蛋白质-蛋白质界面模拟有关的系统。
Conditions were developed for syntheses of β-enamino esters, thioesters, and amides. These reactions involve hydroxybenzotriazole derivatives in buffered media. Illustrative syntheses of some heterocyclic systems are given, including some related to protein–protein interface mimics.