MUSCULAR BLOOD-FLOW DISTRIBUTION PATTERNS AS A FUNCTION OF RUNNING SPEED IN RATS
MUSCULAR BLOOD-FLOW DISTRIBUTION PATTERNS AS A FUNCTION OF RUNNING SPEED IN RATS
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DOI：
10.1152/ajpheart.1982.243.2.h296
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发表时间：
1982-01-01
影响因子：
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通讯作者：
ARMSTRONG, RB
中科院分区：
文献类型：
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作者：
LAUGHLIN, MH;ARMSTRONG, RB
采用放射性标记微球技术测定运动前、跑台步行或以15、30、45、60、75m/min速度跑时大鼠9块主要肌肉内部和之间的肌肉血流量(BF)。在运动中进行稳定行走或跑步1min后进行测量。雄性SD大鼠用2根硅胶导管慢性插管，其中1根在升主动脉经右颈动脉注入微球，1根在左肾动脉取动脉参考血样。运动前结果显示：深部慢抽动肌的BF是周围快肌的3~4倍(比目鱼肌和腓肠肌的BF分别为138和33ml.cntdot)。Min-1.cntdo.分别为100g-1)；混合肌肉中红色部分的BF是白色部分的3-4倍(例如，红色和白色腓肠肌的BF分别为54和18ml.cntdot)。Min-1.cntdo.分别为100g~(-1)和100g~(-1)；BF与肌肉和其慢收缩氧化纤维数量之间存在直接关系(P<；0.05)。结果表明：在所研究的最慢速度下(15m/min)，红色部分的BF增加，而白色部分的BF减少；当流量为39ml/min时，所有肌肉(比目鱼肌除外)的BF都在以75m/min的速度跑时增加。100g-1.cntdo.Min-1(白色腓肠肌)至321(股中间肌)；在所有跑步速度下，对肌肉的BF增加与肌肉的快抽动、高氧化纤维群直接相关；而对内脏组织和脂肪的BF在运动中减少。
Muscle blood flow (BF) was measured using the radiolabeled microsphere technique within and among 9 major muscles of rats before exercise and during treadmill walking or running at speeds of 15, 30, 45, 60 and 75 m/min. Measurements were made during exercise after 1 min of steady walking or running. Male Sprague-Dawley rats were chronically instrumented with 2 Silastic catheters, one in the ascending aorta via the right carotid artery for microsphere infusion and one in the left renal artery for arterial reference blood sample withdrawal. The preexercise results showed the following: BF to deep slow-twitch muscles was 3-4 times that to peripheral fast muscles (e.g., soleus and gastrocnemius BF were 138 and 33 ml .cntdot. min-1 .cntdot. 100 g-1, respectively); BF to red portions within mixed muscles were 3-4 times that to white portions (e.g., red and white gastrocnemius BF were 54 and 18 ml .cntdot. min-1 .cntdot. 100 g-1, respectively); and there was a direct relationship (P < 0.05) between BF to muscles and their slow-twitch oxidative fiber populations. The results obtained during exercise showed the following: at the slowest speed studied (15 m/min) BF to the red portions of muscles increased, whereas BF to the white portions of the same muscles decreased; BF to all muscles (except soleus) were increased during running at 75 m/min when there was a range of flows of 39 ml .cntdot. 100 g-1 .cntdot. min-1 (white gastrocnemius) to 321 (vastus intermedius); at all running speeds the increases in BF to muscles were directly related to the fast-twitch, high-oxidative fiber populations of the muscles; and BF to visceral tissues and fat were decreased during exercise.