Evaluation of moyamoya disease in CT angiography using ultra-high-resolution computed tomography: Application of deep learning reconstruction
Evaluation of moyamoya disease in CT angiography using ultra-high-resolution computed tomography: Application of deep learning reconstruction
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DOI：
10.1016/j.ejrad.2022.110294
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发表时间：
2022-04-12
影响因子：
3.3
通讯作者：
Nakamoto, Yuji
中科院分区：
文献类型：
--
作者：
Fukushima, Yasuhiro;Fushimi, Yasutaka;Nakamoto, Yuji
目的：本研究的目的是检查使用混合迭代重建（Hybrid-IR）、基于模型的迭代重建（MBIR）和深度学习重建（DLR）重建烟雾病（MMD）的超高分辨率计算机断层扫描血管造影（UHR CTA）图像的评估。方法：这项经机构审查委员会批准的回顾性研究纳入了 2018 年 1 月至 2020 年 7 月期间接受 UHR CTA 的临床疑似 MMD 患者。采用三种重建方法重建 CTA 图像。与数字减影血管造影相比，评估了定性可视化。定量评估包括边缘清晰度、半峰全宽 (FWHM)、血管对比度和组织信噪比 (SNRtissue) 的评估。采用单因素方差分析来分析差异。此外，还评估了重建时间。结果：33 侧 CTA 的定性评估在重建方法之间没有显着差异。在对 54 名患者进行的定量评估中，Hybrid-IR 大脑中动脉左右皮质段的边缘清晰度明显高于其他重建。 MBIR 和 DLR 之间没有发现显着差异。 Hybrid-IR 的 STA-MCA 旁路边缘清晰度明显高于 MBIR，但 Hybrid-IR 和 DLR 之间没有显着差异。 STA-MCA 的 FWHM 显示三种重建方法之间没有显着差异。 DLR 显示了最高 SNR 的组织。重建所需的时间为 Hybrid-IR 40 s，MBIR 2580 s，DLR 180 s。结论：结合 DLR 的 UHR CTA 在临床可行的重建时间内充分显示了 MMD 患者的血管。
Purpose: The aim of this study was to examine the evaluation of ultra-high-resolution computed tomography angiography (UHR CTA) images in moyamoya disease (MMD) reconstructed with hybrid iterative reconstruction (Hybrid-IR), model-based iterative reconstruction (MBIR), and deep learning reconstruction (DLR). Methods: This retrospective study with institutional review board approval included patients with clinically suspected MMD who underwent UHR CTA between January 2018 and July 2020. CTA images were recon-structed with three reconstruction methods. Qualitative visualization was evaluated in comparison with digital subtraction angiography. Quantitative evaluation included assessment of edge sharpness, full width at half maximum (FWHM), vessel contrast, and tissue signal-to-noise ratio (SNRtissue). One-way analysis of variance was used to analyze differences. In addition, reconstruction time were assessed. Results: Qualitative evaluation of CTA for 33 sides did not differ significantly between reconstruction methods. In quantitative evaluation for 54 patients, edge sharpness for right and left cortical segments of the middle cerebral artery was significantly higher for Hybrid-IR than for other reconstructions. No significant difference was seen between MBIR and DLR. Edge sharpness for STA-MCA bypass was significantly higher for Hybrid-IR than for MBIR, but no significant difference was seen between Hybrid-IR and DLR. FWHM for STA-MCA showed no significant difference between the three reconstruction methods. DLR displayed the highest SNRtissue. The time required for reconstruction was 40 s for Hybrid-IR, 2580 s for MBIR, and 180 s for DLR. Conclusion: UHR CTA with DLR adequately visualized vessels in patients with MMD within a clinically feasible reconstruction time.