Whole Slide Imaging (WSI) in Pathology: Current Perspectives and Future Directions.
Whole Slide Imaging (WSI) in Pathology: Current Perspectives and Future Directions.
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病理学中的全切片成像（WSI）：当前观点和未来方向。
DOI：
10.1007/s10278-020-00351-z
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发表时间：
2020-08
影响因子：
4.4
通讯作者：
Gupta S
中科院分区：
文献类型：
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作者：
Kumar N;Gupta R;Gupta S
全玻片成像(WSI)自二十多年前首次提出以来，在病理学领域得到了广泛的应用。美国FDA最近批准WSI系统用于初级外科病理诊断，为这项技术在日常实践中的更广泛接受和应用开辟了道路。数字扫描仪、图像可视化方法以及人工智能衍生算法与这些系统的集成方面的持续技术进步为其较新的应用提供了机会。它的好处数不胜数，例如易于通过互联网访问，避免物理存储空间，以及没有染色质量恶化或载玻片破裂的风险。各种障碍，如高成本，技术故障，以及专业人士对采用一项新技术的犹豫，阻碍了它在病理学中的应用。本文综述了WSI的技术方面，它在诊断病理学、培训和研究中的应用，以及未来的展望。它强调了在日常实践中推迟使用这项技术的好处、局限性和挑战。这篇综述的目标是学生、住院医生和初级病理学家，让他们更好地熟悉最先进技术的关键方面，并使他们能够明智地实施WSI。
Whole slide imaging (WSI), ever since its first introduction about two decades ago, has been validated for a number of applications in the field of pathology. The recent approval of US FDA to a WSI system for use in primary surgical pathology diagnosis has opened avenues for wider acceptance and application of this technology in routine practice. The ongoing technological advances in digital scanners, image visualization methods, and the integration of artificial intelligence-derived algorithms with these systems provide opportunities of its newer applications. Its benefits are innumerable such as ease of access through internet, avoidance of physical storage space, and no risk of deterioration of staining quality or breakage of slides to name a few. Various barriers such as the high cost, technical glitches, and professional hesitation to adopt a new technology have hindered its use in pathology. This review article summarizes the technical aspects of WSI, its applications in diagnostic pathology, training, and research along with future perspectives. It highlights the benefits, limitations, and challenges delaying the use of this technology in routine practice. The review is targeted at students, residents, and budding pathologists to better acquaint them with the key aspects of state-of-the-art technology and enable them to implement WSI judiciously.
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影响因子：
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作者：
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影响因子：
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作者：
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通讯作者：
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