Differences between home blood pressure and strictly measured office blood pressure and their determinants in Japanese men
Differences between home blood pressure and strictly measured office blood pressure and their determinants in Japanese men
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DOI：
10.1038/s41440-020-00533-w
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发表时间：
2020-08-31
影响因子：
5.4
通讯作者：
Ueshima, Hirotsugu
中科院分区：
文献类型：
--
作者：
Kadowaki, Sayaka;Kadowaki, Takashi;Ueshima, Hirotsugu
传统的办公室血压(OBP)和家庭血压(HBP)测量经常不一致。本研究的目的是(1)检验在测量前有足够休息时间的严格测量的OBP值(st-OBP)是否在群体水平上与HBP具有可比性；(2)在个体水平上确定HBP和st-OBP之间的差异是否有特定的决定因素。对1056名年龄在40-79岁之间的男性的数据进行了分析。休息5分钟后，测量两次ST-OBP。连续7天每天早晨休息2分钟后测量HBP。为了确定与Delta SBP相关的因素(HBP减去ST-OBP测量值)，进行了多元线性回归分析和协方差分析。在人群水平上，ST-OBP和HBP具有可比性(136.5比137.2毫米汞柱)，Delta SBP有所不同，标准偏差为13.5毫米汞柱。吸烟与更大的Delta SBP相关，而不考虑抗高血压药物的使用，BMI与使用降压药的参与者更大的Delta SBP相关。在服用降压药的参与者中，最高BMI三分位数类别的调整后平均Delta SBP为4.6毫米汞柱。ST-OBP和HBP测量在种群水平上具有可比性，尽管Delta SBP的分布相当广泛。吸烟者和服用降压药的肥胖男性的HBP高于st-OBP，这表明他们的血压水平有被低估的风险。因此，这一群体将受益于增加HBP测量。
Conventional office blood pressure (OBP) and home blood pressure (HBP) measurements are often inconsistent. The purpose of this research was (1) to test whether strictly measured OBP values with sufficient rest time before measurement (st-OBP) is comparable to HBP at the population level and (2) to ascertain whether there are particular determinants for the difference between HBP and st-OBP at the individual level. Data from a population-based group of 1056 men aged 40-79 years were analyzed. After a five-min rest, st-OBP was measured twice. HBP was measured after a 2-min rest every morning for seven consecutive days. To determine factors related to Delta SBP (HBP minus st-OBP measurements), multiple linear regression analyses and analyses of covariance were performed. While st-OBP and HBP were comparable (136.5 vs. 137.2 mmHg) at the population level, Delta SBP varied with a standard deviation of 13.5 mmHg. Smoking was associated with a larger Delta SBP regardless of antihypertensive usage, and BMI was associated with a larger Delta SBP in participants using antihypertensive drugs. The adjusted mean Delta SBP in the highest BMI tertile category was 4.6 mmHg in participants taking antihypertensive drugs. st-OBP and HBP measurements were comparable at the population level, although the distribution of Delta SBP was considerably broad. Smokers and obese men taking antihypertensive drugs had higher HBP than st-OBP, indicating that their blood pressure levels are at risk of being underestimated. Therefore, this group would benefit from the addition of HBP measurements.