Intake of Dried Bonito Broth Flavored with Dextrin Solution Induced Conditioned Place Preference in Mice
Intake of Dried Bonito Broth Flavored with Dextrin Solution Induced Conditioned Place Preference in Mice
复制标题
摄入用糊精溶液调味的干鲣鱼汤诱导小鼠条件性位置偏好
DOI：
10.1271/bbb.110388
复制
发表时间：
2011
期刊：
影响因子：
--
通讯作者：
T. Fushiki
中科院分区：
文献类型：
--
作者：
Hiroya Kawasaki;Atsuko Yamada;Ryota Fuse;T. Fushiki
我们调查，以确定是否干鲣鱼肉汤风味诱导使用条件性位置偏爱（CPP）测试的增强效果。只有干鲣鱼肉汤没有诱导CPP。蔗糖在20%溶液中诱导CPP。21.86%糊精溶液（与20%蔗糖溶液具有相同的卡路里含量）不诱导CPP，但用干鲣鱼肉汤（BD）调味的糊精溶液诱导CPP。含有与BD中相同浓度的糊精、NaCl、IMP、GMP和氨基酸的AD溶液倾向于增加在条件箱中花费的时间，但不显著。芳香族化合物，如柠檬醛，香草醛，和薄荷醇调味的AD解决方案没有诱导CPP，而AD解决方案补充干鲣鱼调味剂诱导CPP。在嗅觉神经切断的小鼠中，自发摄入BD不会诱导CPP。这些结果表明，芳香档案的干鲣鱼肉汤中起着重要的作用，BD诱导的CPP。
We investigated to determine whether dried bonito broth flavor induces a reinforcing effect using the conditioned place preference (CPP) test. Only dried bonito broth did not induce CPP. Sucrose induced CPP in 20% solution. A 21.86% dextrin solution, with the same calorie content as the 20% sucrose solution, did not induce CPP, but a dextrin solution flavored with dried bonito broth (BD) induced CPP. An AD solution containing the same concentrations of dextrin, NaCl, IMP, GMP, and amino acids as found in BD tended to increase the time spent in the conditioned box but did not significantly. Aromatic compounds, such as citral, vanillin, and menthol flavored AD solutions did not induce CPP, whereas an AD solution supplemented with dried bonito flavoring agent induced CPP. In mice with transected olfactory nerves, CPP was not induced by voluntary intake of BD. These results suggest that the aromatic profile of the dried bonito broth plays an important role in BD-induced CPP.