THE EPIDEMIOLOGY OF SARCOIDOSIS IN ROCHESTER, MINNESOTA - A POPULATION-BASED STUDY OF INCIDENCE AND SURVIVAL
THE EPIDEMIOLOGY OF SARCOIDOSIS IN ROCHESTER, MINNESOTA - A POPULATION-BASED STUDY OF INCIDENCE AND SURVIVAL
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DOI：
10.1093/oxfordjournals.aje.a114313
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发表时间：
1986-05-01
影响因子：
5
通讯作者：
KURLAND, LT
中科院分区：
文献类型：
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作者：
HENKE, CE;HENKE, G;KURLAND, LT
利用罗切斯特流行病学项目的独特数据资源，对临床诊断的结节病进行了一项基于社区的研究。在这项基于人群的研究中，对 1946 年至 1975 年间首次诊断出的 75 名明尼苏达州罗彻斯特市结节病居民（发病队列）进行了追踪，追踪了他们截至 1982 年 1 月 1 日为止在社区的全面医疗记录。经年龄和性别调整后，结节病发病率为每 10 万人年 6.1 例。结节病的年龄调整发病率在男性（5.9）和女性（6.3）中相似，发病高峰在男性 30 至 39 岁（18.7）和女性 40 至 49 岁（15.6）。 1946 年至 1975 年期间，女性结节病发病率呈长期上升趋势，活检记录病例的数量和百分比显着增加。结节病发病率的季节性变化很小，罗切斯特 31% 的病例在春季（3 月至 5 月）诊断出季节性高峰。 与美国中北部地区相比，该结节病发病队列的生存率未受影响。
Using the unique data resources of the Rochester Epidemiology Project, a community-based study of clinically diagnosed sarcoidosis was conducted. In this population-based study, the 75 Rochester, Minnesota, residents with sarcoidosis initially diagnosed between 1946 and 1975 (incidence cohort) were followed through their comprehensive medical records in the community to January 1, 1982. The age- and sex-adjusted incidence of sarcoidosis was 6.1 per 100,000 person-years. The age-adjusted incidence of sarcoidosis was similar in males (5.9) and females (6.3), with a peak incidence in males 30 to 39 years old (18.7) and in females 40 to 49 years old (15.6). A secular increase in sarcoidosis incidence was noted in the period 1946-1975 for females, with a marked increase in the number and percentage of biopsy-documented cases. Seasonal variation in sarcoidosis incidence was minimal, with a seasonal peak of 31% of the Rochester cases being diagnosed during the spring (March-May). Survival, compared with that of the North Central United States, was unimpaired in this sarcoidosis incidence cohort.