Structures from the Mesophase: MicroED Targets Crystals Extracted from LCP.

Structures from the Mesophase: MicroED Targets Crystals Extracted from LCP.
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中间相结构:MicroED 目标是从 LCP 中提取的晶体。

DOI:
10.1016/j.str.2020.09.005
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发表时间:
2020
期刊:
Structure (London, England : 1993)
影响因子:
--
通讯作者:
Rodriguez,JoseA
Rodriguez,JoseA
中科院分区:
--
文献类型:
--
作者:
Gallagher-Jones,Marcus;Rodriguez,JoseA

文献摘要

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从立方相(LCP)中生长的纳米晶体中确定蛋白质结构是一种很有前途的晶体学方法。在这一期的结构,朱等。(2020)从单油酸甘油酯LCP的致密基质中提取晶体,通过微电子衍射(MicroED)进行询问,并产生蛋白酶K的2 π结构。
The determination of protein structures from nanocrystals grown in lipidic cubic phase (LCP) is a promising crystallographic approach. In this issue ofStructure, Zhu et al. (2020) extract crystals from the dense matrix of monoolein LCP for interrogation by micro electron diffraction (MicroED) and yield a 2 Å structure of Proteinase K.