Evidence for Transition From Light Chain Deposition Disease by Immunofluorescence-Only to Classic Light Chain Deposition Disease.
Evidence for Transition From Light Chain Deposition Disease by Immunofluorescence-Only to Classic Light Chain Deposition Disease.
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DOI：
10.1016/j.ekir.2021.03.002
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发表时间：
2021-05
影响因子：
6
通讯作者：
Alexander MP
中科院分区：
文献类型：
--
作者：
Nasr SH;Leung N;Heybeli C;Cornell LD;Alexander MP
方法从Mayo诊所的肾脏病理档案中发现3例移植肾LCDD患者，其中序贯方案和/或适应症活检标本显示从LCDD-IF过渡到经典LCDD(LCDD IF/EM)。两名患者被移植并在美国明尼苏达州罗切斯特市的梅奥诊所进行随访，移植活检标本通常在植入时、3至4个月、1、2和5年进行。第三名患者被移植到其他地方。临床数据、治疗和随访均从患者的电子病历中获得。
MethodsThree patients with LCDD in the renal allograft in whom sequential protocol and/or indication biopsy specimens showed transition from LCDD-IF to classic LCDD (LCDD IF/EM) were identified from the renal pathology archives at Mayo Clinic. Two patients were transplanted and followed at Mayo Clinic, Rochester, Minnesota, USA, where protocol transplant biopsy specimens are generally performed at implantation, 3 to 4 months, and at 1, 2, and 5 years. The third patient was transplanted elsewhere. Clinical data, treatment, and follow-up were obtained from the patients’ electronic medical records.
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