Foveal dysfunction and central visual field loss in glaucoma

Foveal dysfunction and central visual field loss in glaucoma
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DOI:
10.1001/archopht.116.9.1169
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发表时间:
1998-09-01
影响因子:
--
通讯作者:
Weidenthal, DT
Weidenthal, DT
中科院分区:
其他
文献类型:
--
作者:
Weiner, A;Ripkin, DJ;Weidenthal, DT

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目的:探讨神经节细胞层远端中央凹功能是否为青光眼中央视野功能的独立预测指标。单位:大学附属医院和私人诊所。受试者:27眼(27例)常压青光眼,10眼(10例)原发性开角型青光眼,47眼(47例)正常受试者。干预措施和主要结果测量:中央凹锥体视网膜电图(ERG)振幅,相对视杯与椎间盘面积及其与Humphrey全阈值30-2视野中心4点平均总偏差(C4MTD)和模式偏差(C4MPD)的关系。结果:37只青光眼中14只(37.8%)眼中央凹锥体ERG波幅低于正常,青光眼组低于正常眼(P
Objective: To determine whether foveal function distal to the ganglion cell layer is an independent predictor of central visual field function in glaucoma.Setting: University affiliated hospital and private practice.Participants: Twenty-seven eyes (27 patients) with normal-pressure glaucoma, 10 eyes (10 patients) with primary open-angle glaucoma, and 47 eyes of 47 matched normal volunteers.intervention and Main Outcome Measures: Foveal cone electroretinogram (ERG) amplitude, relative optic cup to disc area and their relations to Humphrey full-threshold 30-2 visual field central 4-point mean total deviation (C4MTD) and pattern deviation (C4MPD).Results: Foveal cone ERG amplitude was subnormal in 14 (37.8%) of the 37 glaucomatous eyes and lower in the glaucoma group compared with normal eyes (P