Peptic ulcer and Helicobacter pylori
Peptic ulcer and Helicobacter pylori
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DOI：
10.1016/s0889-8553(05)70146-1
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发表时间：
2000-12-01
影响因子：
3.7
通讯作者：
Cohen, H
中科院分区：
文献类型：
--
作者：
Cohen, H
本文综述了幽门螺杆菌与消化性溃疡病（PUD）关系的主要证据。然而，PUD的流行病学还在不断变化，将来，H。幽门螺杆菌可能成为一个不太普遍的因素，因为它现在是在出血与简单的溃疡。不幸的是，一些诊断测试在出血性溃疡的准确性可能低于无并发症的溃疡。与H. pylori毒力因子在溃疡病中的作用，H. pylori溃疡病，H. pylori、NSAIDS和溃疡，以及H.幽门溃疡的审查。
The evidence in support of the dominant role of Helicobacter pylori in association with peptic ulcer disease (PUD) is reviewed. The epidemiology of PUD is in flux, however, and, in the future, H. pylori may become a less prevalent factor, because it now is in bleeding versus uncomplicated ulcers. Unfortunately, the accuracy of some diagnostic tests in bleeding ulcers may be lower than in uncomplicated ulcers. Concepts related to H. pylori virulence factors in ulcer disease, the pathophysiology of H. pylori ulcer disease, the interrelationships among H. pylori, NSAIDS, and ulcers, and the management of H. pylori ulcers are reviewed.