Phonological blocking during picture naming in dementia of the Alzheimer type.

Phonological blocking during picture naming in dementia of the Alzheimer type.
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阿尔茨海默型痴呆症图片命名过程中的语音阻塞。

DOI:
10.1037/0894-4105.18.3.526
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发表时间:
2004
期刊:
Neuropsychology.
影响因子:
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通讯作者:
Multhaup,KristiS
Multhaup,KristiS
中科院分区:
--
文献类型:
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作者:
Faust,MarkE;Balota,DavidA;Multhaup,KristiS

文献摘要

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阿尔茨海默型痴呆症患者(DAT;n=53,年龄55-91岁)、健康老年人(n=75,年龄59-91岁)和年轻人(n=24,年龄18-24岁)进行单词提示图片命名任务。词素是中性的(准备好的),在语义上或语音上相关,或与正确的图片名称无关。在反应潜伏期中,所有组都产生了等量的无关词干扰和语义启动效应。然而,错误分析显示,与DAT相关的语音阻塞增加。结果表明,DAT中的图片命名错误至少部分是由于对其他高活性替代的抑制性控制减少而导致对物体名称的语音表征的通达能力下降所致。
Individuals with dementia of the Alzheimer type (DAT; n= 53, ages 55–91), healthy older adults (n= 75, ages 59–91), and younger adults (n= 24, ages 18–24) performed a word-primed picture-naming task. Word primes were neutral (ready), semantically or phonologically related, or unrelated to the correct picture name. All groups produced equivalent unrelated-word interference and semantic priming effects in response latencies. However, analysis of errors revealed a DAT-related increase of phonological blocking. The results suggest that picture-naming errors in DAT are due, at least in part, to a breakdown in access to phonological representations of object names as a consequence of reduced inhibitory control over other highly active alternatives.