Image-based assessment of uncertainty in quantification of carotid lumen
Image-based assessment of uncertainty in quantification of carotid lumen
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DOI：
10.1117/1.jmi.5.3.034003
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发表时间：
2018-07-01
影响因子：
2.4
通讯作者：
Hennemuth, Anja
中科院分区：
文献类型：
--
作者：
Kaufhold, Lilli;Harloff, Andreas;Hennemuth, Anja
血管管腔直径的测量通常被用来确定颈动脉粥样硬化性疾病的程度。然而，量化结果随成像技术和采集设置的不同而不同。我们的目标是提供一个工具来量化不同图像数据集上的管腔直径，并给出量化不确定度的估计，以便在评估和比较测量时考虑这些不确定度。对于血管管腔的分割，我们提出了一种基于光线投射技术和部分体积校正的算法。此外，我们还提出了一种对管腔直径进行分析和探索的方案。最后，我们提出了一个临床相关的应用场景，其中我们探讨了具有严重颈动脉粥样硬化斑块的颈动脉血管的相应CT血管成像、增强磁共振血管成像、飞行时间和减影图像中的管腔直径估计之间的一致性。(C)2018年光学仪器工程师学会(SPIE)
Measurements of the vessel lumen diameter are often used to determine the degree of atherosclerotic disease in carotid arteries. However, quantification results vary with imaging technique and acquisition settings. We aim at providing a tool that quantifies the lumen diameter on different image datasets and gives an estimate of quantification uncertainties, so that they can be taken into consideration when evaluating and comparing measurements. For the segmentation of the vessel lumen, we present an algorithm using ray-casting techniques and partial volume correction. We furthermore propose a scheme for the analysis and exploration of the lumen diameter. Finally, we present a clinically relevant application scenario, in which we explore agreement between lumen diameter estimations in corresponding computed tomography angiography, contrast-enhanced magnetic resonance angiography, time-of-flight, and subtraction images of carotid vessels with severe carotid atherosclerotic plaques. (C) 2018 Society of Photo-Optical Instrumentation Engineers (SPIE)