Debridement of the noninfected wound
Debridement of the noninfected wound
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DOI：
10.1016/j.jvs.2010.06.006
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发表时间：
2010-09-01
影响因子：
4.3
通讯作者：
Attinger, Christopher E.
中科院分区：
文献类型：
--
作者：
Cornell, Rhonda S.;Meyr, Andrew J.;Attinger, Christopher E.
伤口清创术的效用已扩展到包括所有慢性伤口的管理，即使在没有感染和严重坏死的情况下。伤口基底上的生物膜、金属蛋白酶和伤口边缘的衰老细胞不可逆地改变伤口愈合的生理学，并促成病理性慢性炎症环境。本综述的目的是为外科医生提供对非感染伤口清创过程的基本了解。（J Vase Surg 2010;52：31S-6S.）
The utility of wound debridement has expanded to include the management of all chronic wounds, even in the absence of infection and gross necrosis. Biofilm, metalloproteases on the wound base, and senescent cells at the wound edge irreversibly change the physiology of wound healing and contribute to a pathologic, chronic inflammatory environment. The objective of this review is to provide surgeons with a baseline understanding of the processes of debridement in the noninfected wound. (J Vase Surg 2010;52:31S-6S.)