Stress-related factors in cannabis use and misuse: implications for prevention and treatment.
Stress-related factors in cannabis use and misuse: implications for prevention and treatment.
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DOI：
10.1016/j.jsat.2008.08.005
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发表时间：
2009-06
影响因子：
3.9
通讯作者：
Sinha R
中科院分区：
文献类型：
--
作者：
Hyman SM;Sinha R
我们研究了压力作为大麻使用/滥用的风险因素和动机的作用。对从PsychINFO和MEDLINE数据库收集的研究进行了系统回顾。研究结果表明，大麻通常被用作一种应对压力的策略。消极的生活事件、创伤和不适应的应对都与消费有关。在检查慢性大麻使用与实验性大麻使用相比，用于应对压力的大麻使用最为明显。虽然许多人可能能够使用大麻而没有后果，但似乎有一小部分人经历了更大的生活压力，他们可能更有可能使用大麻来应对压力。这些人上瘾的风险最大。长期使用大麻可能会增强与压力相关的使用/滥用大麻的动机，并与决策缺陷和脑应激通路的改变有关，这可能会加剧强迫性药物寻求并使个人对压力相关的药物使用敏感。总的来说，压力应对干预措施和减少危害的重点是减少摄入量可能有助于预防和恢复工作。
We examined the role of stress as a risk factor and motivation for cannabis use/misuse. A systematic review of studies gathered from PsychINFO and MEDLINE databases was conducted. Findings suggest that cannabis is commonly used as a stress-coping strategy. Negative life events, trauma, and maladaptive coping were all related to consumption. Cannabis use for stress-coping purposes was most evident when examining chronic as compared with experimental use. While many individuals may be able to use cannabis without consequences, there appears to be a subset of individuals who experience greater life stress and who may be more likely to use for stress-coping purposes. These individuals may be at greatest risk for addiction. Chronic use may potentiate stress-related motivation to use/abuse cannabis and is associated with decision making deficits and alterations in brain-stress pathways that may exacerbate compulsive drug-seeking and sensitize individuals to stress-related drug use. Overall, stress-coping interventions and harm reduction focused on reducing the amount ingested may facilitate prevention and recovery efforts.