Physical activity and diabetes risk in postmenopausal women
Physical activity and diabetes risk in postmenopausal women
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DOI：
10.1016/j.amepre.2004.09.012
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发表时间：
2005-01-01
影响因子：
5.5
通讯作者：
Howard, BV
中科院分区：
文献类型：
--
作者：
Hsia, J;Wu, LL;Howard, BV
背景资料：评估体力活动独立预测绝经后非洲裔美国人、西班牙裔、亚洲人2型糖尿病风险的假设。和高加索妇女。方法：我们在妇女健康倡议观察性研究中前瞻性地评估了2型糖尿病、步行和基线总体力活动之间的关系。基线数据收集于1994年9月至1998年12月之间;糖尿病事件确定至2002年8月。在高加索人、非裔美国人、西班牙裔和亚洲/太平洋岛民妇女中，评估了身体活动类别中自我报告的糖尿病风险比（经体重指数（BMI）和其他变量调整后）。2.2%的高加索人、6.2%的非洲裔美国人、4.5%的西班牙裔美国人、3%的亚洲人报告了糖尿病事件，在458，018名女性-年的随访中，5.7%的美国印第安人焦虑（各种族p < 0.0001）。在高加索女性中，步行（多变量校正的风险比为1.00，0.85，0.87，0.75，0.74;对于运动五分位数的趋势，p < 0.001）和总体力活动评分（风险比为1.00，0.88，0.74，0.80，0.67; p = 0.002）与糖尿病风险呈强负相关。在BMI调整的模型中，体力活动量较高的非裔美国女性比体力活动量最低的女性患糖尿病的可能性更小。调整英亩和多种危险因素后，然而，体力活动和糖尿病的风险之间没有显着的关联是明显的非裔美国人，西班牙裔，或亚洲women.Conclusions：这些研究结果表明，一个更强大的和更独立的关联，体力活动与糖尿病的发展在高加索妇女比少数民族妇女。但也可以解释为对少数群体妇女的风险估计不太准确或偶然性的作用。(C)2005年美国预防医学杂志。
Background: To evaluate the hypothesis that physical activity independently predicts type 2 diabetes risk in postmenopausal African-American, Hispanic, Asian. and Caucasian women.Methods: We prospectively evaluated the relationship between incident type 2 diabetes, walking, and total physical activity at baseline in the Women's Health Initiative Observational Study. Baseline data were collected between September 1994 and December 1998; incident diabetes was identified through August 2002. Hazard ratios for self-reported diabetes adjusted for body mass index (BMI) and other variables were evaluated across categories of physical activity in Caucasian, African-American, Hispanic, and Asian/Pacific Islander women.Results: Incident diabetes was reported by 2.2% of Caucasian, 6.2% of African-American, 4.5% of Hispanic, 3% of Asian, and 5.7% of American Indian worrien (p < 0.0001 across ethnic groups) during 458,018 woman-years of follow-up. Among Caucasian women, walking (multivariate-adjusted hazard ratios 1.00, 0.85, 0.87, 0.75, 0.74; p < 0.001 for trend across: exercise quintiles) and total physical activity score (hazard ratios 1.00, 0.88, 0.74, 0.80, 0.67; p = 0.002) demonstrated a strong inverse relationship with diabetes risk. In BMI-adjusted models, African-American women in higher physical activity categories were less likely to develop diabetes than women in the lowest physical activity; category. After adjusting for acre and multiple risk factors, however, no significant association between Physical activity and diabetes risk was apparent for African-American, Hispanic, or Asian women.Conclusions: These findings suggest a stronger and more independent association of physical inactivity with development of diabetes in Caucasian women than in minority women. but could also be explained by less precise risk estimates in minority women or the role of chance. (C) 2005 American Journal of Preventive Medicine.