Onset of lactation in the bovine mammary gland: gene expression profiling indicates a strong inhibition of gene expression in cell proliferation
Onset of lactation in the bovine mammary gland: gene expression profiling indicates a strong inhibition of gene expression in cell proliferation
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DOI：
10.1007/s10142-008-0074-y
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发表时间：
2008-08-01
影响因子：
2.9
通讯作者：
Zhao, Feng-Qi
中科院分区：
文献类型：
--
作者：
Finucane, Kiera A.;McFadden, Thomas B.;Zhao, Feng-Qi
从妊娠晚期到哺乳期，乳腺的功能和代谢发生了巨大的变化。为了更好地了解这些变化背后的分子事件，我们分析了分娩前5天和分娩后10天左右牛乳腺组织中约23，000个基因转录物的表达谱。在有符号倍数变化>= 2或
The mammary gland undergoes dramatic functional and metabolic changes during the transition from late pregnancy to lactation. To better understand the molecular events underlying these changes, we analyzed expression profiles of approximately 23,000 gene transcripts in bovine mammary tissue about day 5 before parturition and day 10 after parturition. At the cutoff criteria of the signed fold change >= 2 or