The effects of low-level prenatal lead exposure on birth outcomes
The effects of low-level prenatal lead exposure on birth outcomes
复制标题
低水平产前铅暴露对出生结局的影响
DOI：
10.1016/j.envpol.2012.12.013
复制
发表时间：
2013-04-01
影响因子：
8.9
通讯作者：
Tian, Ying
中科院分区：
文献类型：
--
作者：
Xie, Xin;Ding, Guodong;Tian, Ying
早期铅暴露可能是胎儿生长的一个危险因素，但对低水平产前铅暴露对出生结局的影响知之甚少。我们测量了母亲和脐带血铅水平，并研究了它们与出生结果的关系。2010年至2011年，从莱州湾南岸的农村地区招募了母婴对（n = 252）。母亲和脐带血铅的中位数分别为3.20和2.52微克/分升。母亲血铅暴露增加与出生体重下降相关（β = -148.99; 95%CI，-286.33至-11.66），脐带血铅水平与出生身长呈显著负相关（β = -0.84; 95%CI，-1.52至-0.16）。低水平的产前铅暴露可能会对胎儿生长产生不利影响。这些结果可能对公众健康很重要，并对推荐的血铅水平有影响。(C)2013爱思唯尔有限公司保留所有权利。
Exposure to lead early in life may be a risk factor for fetal growth, but little is known about the effects of low-level prenatal lead exposure on birth outcomes. We measured maternal and cord blood lead levels and examined their associations with birth outcomes. Mother infant pairs (n = 252) were recruited from a rural area located on the south coast of Laizhou Bay between 2010 and 2011. The median levels of maternal and cord blood lead were 3.20 and 2.52 mu g/dL, respectively. Increasing maternal blood lead exposure was associated with decreasing birth weight (beta = -148.99; 95% CI, -286.33 to -11.66), and a significant negative relationship was found between cord blood lead levels and birth length (beta = -0.84; 95% CI, -1.52 to -0.16). Low-level prenatal lead exposure may adversely affect fetal growth. These results may be important for public health and have implications regarding the recommended blood lead levels. (C) 2013 Elsevier Ltd. All rights reserved.