High-soluble-fiber foods in conjunction with a telephone-based, personalized behavior change support service result in favorable changes in lipids and lifestyles after 7 weeks
High-soluble-fiber foods in conjunction with a telephone-based, personalized behavior change support service result in favorable changes in lipids and lifestyles after 7 weeks
复制标题
DOI：
10.1016/s0002-8223(02)90116-1
复制
发表时间：
2002-04-01
影响因子：
--
通讯作者：
Slonim, AB
中科院分区：
文献类型：
--
作者：
Kris-Etherton, PM;Taylor, DS;Slonim, AB
目的评估是否干预的食物高可溶性纤维从车前子和/或燕麦加上电话为基础的，个性化的行为改变支持服务，改善血脂和eleventlingcholesterol-管理生活方式的变化与常规care.Design 7周的随机对照干预。干预干预组每天食用4份高纤维食物，每周与私人教练进行电话交谈，私人教练提供支持和指导，使生活方式的改变与国家胆固醇教育计划（NCEP）的胆固醇-降低指导方针。常规护理组收到一份描述NCEP Step-1饮食的讲义。主要结果测量血清脂质和脂蛋白以及自我报告的生活方式变化。统计分析对于生理和饮食变化，应用重复测量的混合线性模型。使用协方差分析简化模型，其中年龄（岁）为协变量。结果干预组总胆固醇（TC）下降5.6%，低密度脂蛋白（LDL）下降7.1%，低密度脂蛋白/高密度脂蛋白（HDL）下降5.6%，甘油三酯（TG）下降14.2%（P
Objective To evaluate whether an intervention of foods high in soluble fiber from psyllium and/or oats plus a telephone-based, personalized behavior change support service improves serum lipids and elicits cholesterol-managing lifestyle changes vs usual care.Design 7-week randomized, controlled intervention.Subjects/setting 150 moderately hypercholesterolemic men and women, age range 25 to 70 years.Intervention The intervention group consumed 4 servings/day of high-fiber foods and had weekly telephone conversations with a personal coach who offered support and guidance in making lifestyle changes consistent with the National Cholesterol Education Program's (NCEP) cholesterol-lowering guidelines. The usual care group received a handout describing the NCEP Step-1 diet.Main outcome measures Serum lipids and lipoproteins and self-reported lifestyle changes.Statistical analyses For physiologic and dietary changes, mixed linear models for repeated measures were applied. Models were simplified using analysis of covariance where age in years was the covariate. Traditional general linear models were used to assess lifestyle changes.Results In the intervention group total cholesterol (TC) decreased 5.6%, low-density lipoprotein (LDL) cholesterol 7.1%, LDL/high-density lipoprotein (HDL) cholesterol ratio 5.6%, and triglycerides (TG) 14.2% (P