Cardiac Allograft Function During the First Year after Transplantation in Rejection-Free Children and Young Adults
Cardiac Allograft Function During the First Year after Transplantation in Rejection-Free Children and Young Adults
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DOI:
10.1161/circimaging.112.976613
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发表时间:
2012-11-01
影响因子:
7.5
通讯作者:
Singh, Tajinder P.
中科院分区:
文献类型:
--
作者:
Lunze, Fatima I.;Colan, Steven D.;Singh, Tajinder P.
Background-Allograft dysfunction is a common finding early after heart transplant (HT). We sought to assess the recovery of left (LV) and right ventricular (RV) function during the first year after HT in children and young adults using pulsed-wave tissue Doppler imaging.Methods and Results-We analyzed serially performed echocardiography in 44 pediatric HT recipients (median age: 7.3 years at HT) who remained rejection-free during the first year post-transplant. Age-based normative values for systolic (S'), early-diastolic (E'), and late-diastolic (A') velocities obtained using pulsed-wave tissue Doppler imaging in 380 healthy children were used to transform patient data into z scores. Pulsed-wave tissue Doppler imaging studies