Cardiac Allograft Function During the First Year after Transplantation in Rejection-Free Children and Young Adults

Cardiac Allograft Function During the First Year after Transplantation in Rejection-Free Children and Young Adults
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DOI:
10.1161/circimaging.112.976613
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发表时间:
2012-11-01
影响因子:
7.5
通讯作者:
Singh, Tajinder P.
Singh, Tajinder P.
中科院分区:
医学1区
文献类型:
--
作者:
Lunze, Fatima I.;Colan, Steven D.;Singh, Tajinder P.

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背景 - 同ant函数障碍是心脏移植(HT)后早期的常见发现。我们试图评估HT使用脉冲波组织多普勒成像的HT和年轻人的第一年的左侧(LV)和右心(RV)功能的回收收件人(中位年龄:HT的7.3岁)在移植后第一年保持无排斥。基于年龄的基于年龄的规范值(S'),早期舒张(E')和晚期舒张(A')速度使用脉冲波组织多普勒在380个健康儿童中获得的速度用于将患者数据转化为Z评分。脉冲波组织多普勒成像研究
Background-Allograft dysfunction is a common finding early after heart transplant (HT). We sought to assess the recovery of left (LV) and right ventricular (RV) function during the first year after HT in children and young adults using pulsed-wave tissue Doppler imaging.Methods and Results-We analyzed serially performed echocardiography in 44 pediatric HT recipients (median age: 7.3 years at HT) who remained rejection-free during the first year post-transplant. Age-based normative values for systolic (S'), early-diastolic (E'), and late-diastolic (A') velocities obtained using pulsed-wave tissue Doppler imaging in 380 healthy children were used to transform patient data into z scores. Pulsed-wave tissue Doppler imaging studies