Multiplexed Paper Microfluidics for Titration and Detection of Ingredients in Beverages
Multiplexed Paper Microfluidics for Titration and Detection of Ingredients in Beverages
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DOI：
10.3390/s19061286
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发表时间：
2019-03
期刊：
影响因子：
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通讯作者：
Alisha Prasad;Tiffany Tran;M. Gartia
中科院分区：
文献类型：
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作者：
Alisha Prasad;Tiffany Tran;M. Gartia
在大多数发展中国家，食品安全和获得确保检测食品危害的系统方法是一个重要问题。随着纸基分析设备（µ PAD）作为一种有前途的，快速的，易于使用的，低成本的分析工具的到来，我们展示了一种简单的基于微流体的滴定研究，用于包装果汁的分析。与化学实验室中使用传统玻璃器皿的滴定实验类似，在本研究中，使用纸微流体技术开发了滴定实验，用于分析包装果汁中存在的几种分析物，如pH值，维生素C，糖和防腐剂。过敏原通常发现在乳制品为基础的混合物和非致病性的生化成分负责食品腐败的苹果汁为基础的果汁也被确定。使用纸微流体获得的结果进行了比较，与使用传统的分光光度技术获得的结果。最后，开发了一种基于纸微流体的多路复用传感器，用于在单个平台上分析包装果汁中存在的常见营养成分、过敏原和非致病性副产品。总的来说，本研究中呈现的结果表明，所提出的纸微流体辅助比色多路复用传感器为食品安全应用的现场常规分析提供了快速可靠的工具。
Food safety and access to systematic approaches for ensuring detection of food hazards is an important issue in most developing countries. With the arrival of paper-based analytical devices (µPADs) as a promising, rapid, easy-to-use, and low-cost analytical tool, we demonstrated a simple microfluidic-based titration study for the analysis of packaged fruit juices. Similar, to the titration experiments using traditional glassware in chemistry laboratories, in this study the titration experiments were developed using paper microfluidics for the analysis of several analytes such as pH, vitamin C, sugars, and preservatives present in the packaged fruit juices. The allergen found commonly in dairy based mixtures and the non-pathogenic biochemical component responsible for food spoilage in cider based fruit juices were also determined. The results obtained using paper microfluidics were compared with those obtained using a conventional spectrophotometric technique. Finally, a paper microfluidics based multiplexed sensor was developed for the analysis of common nutritional ingredients, an allergen, and a non-pathogenic byproduct present in packaged fruit juices on a single platform. Overall, the results presented in this study reveal that the proposed paper microfluidic assisted colorimetric multiplexed sensor offers a quick and reliable tool for on-spot routine analysis for food safety applications.