Dietary effects on exercising muscle metabolism and performance by 31P-MRS.
Dietary effects on exercising muscle metabolism and performance by 31P-MRS.
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31P-MRS 饮食对运动肌肉代谢和性能的影响。
DOI：
10.1152/jappl.1994.77.3.1108
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发表时间：
1994
期刊：
影响因子：
--
通讯作者：
Systrom,DM
中科院分区：
文献类型：
--
作者：
Larson,DE;Hesslink,RL;Hrovat,MI;Fishman,RS;Systrom,DM
为了确定饮食如何调节短期运动能力，骨骼肌pH值和生物能量状态进行了检查，在9名健康志愿者的31 P-磁共振波谱。受试者在交叉随机分配的高碳水化合物（HCHO）或高脂肪（HFAT）饮食5天后进行递增的四头肌运动至筋疲力尽，并由2.5天的随意混合饮食间隔。同时测量肺气体交换，每分钟通气量，四头肌pH值和磷酸化电位。在静息和运动高峰时，HCHO组的呼吸交换率和每分钟通气量均高于HFAT组（P < 0.05），反映了更高的CHO利用率。使用HCHO后，峰值耗氧量（VO 2）没有增加（P > 0.05），但运动持续时间为（HCHO为339 +/- 34 s，HFAT为308 +/- 25 s; P < 0.05）。与VO 2相比，HCHO与磷酸肌酸（PCr）/Pi的早期下降平缓相关（HCHO为-4.1 +/- 0.7 x 10（-2）min/ml，HFAT为-5.6 +/- 1.2 x 10（-2）min/ml; P < 0.05）。在两个研究日，PCr/Pi与VO 2的斜率，在PCr阈值之前和之后，与运动时间相关。结果表明，富含CHO的饮食通过对细胞内磷酸化潜力的有益影响来提高运动效率。
To determine how diet modulates short-term exercise capacity, skeletal muscle pH and bioenergetic state were examined by 31P-magnetic resonance spectroscopy in nine healthy volunteers. Subjects performed incremental quadriceps exercise to exhaustion after 5 days of high-carbohydrate (HCHO) or high-fat (HFAT) diet randomly assigned in crossover fashion and separated by a 2.5-day period of ad libitum mixed diet. Simultaneous measurements were made of pulmonary gas exchange, minute ventilation, and quadriceps muscle pH and phosphorylation potential. At rest and peak exercise, respiratory exchange ratio and minute ventilation were higher after HCHO than after HFAT (P < 0.05), reflecting greater CHO utilization. Peak O2 consumption (VO2) was not increased after HCHO (P > 0.05), but exercise duration was (339 +/- 34 s for HCHO vs. 308 +/- 25 s for HFAT; P < 0.05). HCHO was associated with a blunted early fall of phosphocreatine (PCr)/Pi vs. VO2 (-4.1 +/- 0.7 x 10(-2) min/ml for HCHO vs. -5.6 +/- 1.2 x 10(-2) min/ml for HFAT; P < 0.05). On both study days, the slope of PCr/Pi vs. VO2, before and after the PCr threshold, was correlated with exercise time. The results suggest that a diet rich in CHO improves exercise efficiency through beneficial effects on intracellular phosphorylation potential.