A pilot study of functional magnetic resonance imaging brain correlates of deception in healthy young men.
A pilot study of functional magnetic resonance imaging brain correlates of deception in healthy young men.
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一项针对健康年轻男性的大脑功能磁共振成像与欺骗行为的初步研究。
DOI：
10.1176/jnp.16.3.295
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
Mark S. George
中科院分区：
文献类型：
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作者：
F. Kozel;Letty J. Revell;J. Lorberbaum;A. Shastri;Jon D. Elhai;Michael D. Horner;A. Smith;Z. Nahas;D. Bohning;Mark S. George
我们假设在欺骗过程中特定的大脑区域会被激活，这些区域与皮肤电活动（EDA）的变化有关。八个人被要求找出藏在各种物品下的钱。在获得功能性核磁共振成像和EDA记录的同时，受试者对钱的位置给出了真实和虚假的回答。小组分析显示，欺骗过程中眶额皮质（OFCx）和前扣带（AC）显著激活，但个体结果不一致。无论是个体还是群体，EDA都与OFCx和AC的血流变化相关。在欺骗过程中，特定的大脑区域被激活，但目前的技术对个体缺乏良好的预测能力。
We hypothesized that specific brain regions would activate during deception, and these areas would correlate with changes in electrodermal activity (EDA). Eight men were asked to find money hidden under various objects. While functional MRI images were acquired and EDA was recorded, the subjects gave both truthful and deceptive answers regarding the money's location. The group analysis revealed significant activation during deception in the orbitofrontal cortex (OFCx) and anterior cingulate (AC), but individual results were not consistent. Individually and as a group, EDA correlated with blood flow changes in the OFCx and AC. Specific brain regions were activated during deception, but the present technique lacks good predictive power for individuals.