Study on ultrasonic measurement system to detect penetration of boulders
Study on ultrasonic measurement system to detect penetration of boulders
复制标题
超声波检测巨石穿透力的测量系统研究
DOI：
10.1111/iju.12669
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发表时间：
2005
影响因子：
2.6
通讯作者：
M. Ujihira
中科院分区：
文献类型：
--
作者：
Y. Kawamura;N. Aoshima;Yutaka Ito;K. Mizutani;M. Tsurushima;M. Ujihira
目的探讨早晚给药α1‐阻滞剂纳托地尔对下尿路症状改善的差异。方法选取男性夜尿症患者177例，随机分为早晚两组。比较两组患者12周时的国际前列腺症状评分、生活质量指数和夜尿生活质量指数。结果共分析143例患者（上午组70例，晚上组73例），其中34例患者因不同意、不良事件和未出席而退出。夜尿症、生活质量指数和12周夜尿症生活质量指数夜间组明显优于早晨组。在多变量模型中，纳托地尔给药时间和初始夜尿症生活质量指数与夜尿症生活质量指数的变化显著相关。结论夜间给药纳哌地尔治疗有下尿路症状的男性夜尿症效果较好。
ObjectivesTo examine the difference in improvement of lower urinary tract symptoms between morning and evening dosing of α1‐blocker naftopidil.MethodsA total of 177 male patients with nocturia were included in the present study and randomized to morning or evening dosing of naftopidil. The International Prostate Symptom Score, quality of life index and nocturia quality of life index were compared between the two study groups at 12 weeks.ResultsA total of 143 patients (morning group:n= 70, evening group:n= 73) were analyzed as a result of the dropout of 34 patients because of failure to give consent, adverse events and failure to attend. Nocturia, quality of life index and nocturia quality of life index at 12 weeks were significantly better in the evening group compared with the morning group. In a multivariate model, both the dosing time of naftopidil and the initial nocturia quality of life index were significantly associated with change in nocturia quality of life index.ConclusionsEvening dosing of naftopidil seems to be more effective in treating nocturia in male patients with lower urinary tract symptoms.