Presumed hydrogen sulfide-mediated neurotoxicity after streptococcus anginosus group meningitis.

Presumed hydrogen sulfide-mediated neurotoxicity after streptococcus anginosus group meningitis.
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DOI:
10.1097/inf.0b013e3182748fe9
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发表时间:
2013-02
期刊:
The Pediatric infectious disease journal
影响因子:
--
通讯作者:
Willoughby RE Jr
Willoughby RE Jr
中科院分区:
其他
文献类型:
--
作者:
Verma S;Landisch R;Quirk B;Schmainda K;Prah M;Whelan HT;Willoughby RE Jr

文献摘要

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硫化氢(H_2S)是一种环境毒物和气体神经递质。它是由硫磺还原菌和侵袭性病原体包括链球菌群、沙门氏菌和柠檬酸杆菌在肠道中产生的。我们描述了星状链球菌脑膜炎后推测的局部硫化氢神经毒性,用辅助性亚硝酸钠和高压氧治疗。
Hydrogen sulfide (H2S) is an environmental toxicant and gaseous neurotransmitter. It is produced enterically by sulfur-reducing bacteria and invasive pathogens including Streptococcus anginosus group, Salmonella and Citrobacter. We describe putative focal H2S neurotoxicity following S. constellatus meningitis, treated with adjunctive sodium nitrite and hyperbaric oxygen therapy.