The systemin receptor SYR1 enhances resistance of tomato against herbivorous insects
The systemin receptor SYR1 enhances resistance of tomato against herbivorous insects
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DOI：
10.1038/s41477-018-0106-0
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发表时间：
2018-02
期刊：
影响因子：
18
通讯作者：
Lei Wang;Elias Einig;Marilia Almeida-Trapp;M. Albert;J. Fliegmann;A. Mithöfer;H. Kalbacher;G. Felix
中科院分区：
文献类型：
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作者：
Lei Wang;Elias Einig;Marilia Almeida-Trapp;M. Albert;J. Fliegmann;A. Mithöfer;H. Kalbacher;G. Felix
番茄中第一种植物肽激素系统素的发现，使植物激素的概念发生了根本性的变化。此后，许多其他肽已被证明在植物生命的许多方面发挥调节作用，包括生长、发育、受精以及与共生生物的相互作用，，-。系统素是一种源自较大前体蛋白的 18 个氨基酸肽，被认为可以充当传播信号，触发植物在受到食草动物伤害或攻击后观察到的系统防御反应。进一步的工作最终确定了富含亮氨酸的重复受体激酶 (LRR-RK) 作为系统素受体 160 (SR160)。 SR160 是油菜素类固醇不敏感 1 (BRI1) 的番茄同系物，可响应类固醇激素油菜素内酯 - 介导生长和发育的调节。然而，SR160/BRI1 作为系统素受体的作用无法得到其他人的证实，-。在这里，我们证明对系统素的感知取决于一对不同的 LRR-RK，称为 SYR1 和 SYR2。 SYR1 作为真正的系统素受体，以高亲和力和特异性结合系统素。此外，我们还表明，SYR1 的存在虽然对局部和全身伤口反应不是决定性的，但对于防御昆虫食草很重要。
The discovery in tomato of systemin, the first plant peptide hormone,, was a fundamental change for the concept of plant hormones. Numerous other peptides have since been shown to play regulatory roles in many aspects of the plant life, including growth, development, fertilization and interactions with symbiotic organisms, , –. Systemin, an 18 amino acid peptide derived from a larger precursor protein, was proposed to act as the spreading signal that triggers systemic defence responses observed in plants after wounding or attack by herbivores,,. Further work culminated in the identification of a leucine-rich repeat receptor kinase (LRR-RK) as the systemin receptor 160 (SR160),. SR160 is a tomato homologue of Brassinosteroid Insensitive 1 (BRI1), which mediates the regulation of growth and development in response to the steroid hormone brassinolide, –. However, a role of SR160/BRI1 as systemin receptor could not be corroborated by others, –. Here, we demonstrate that perception of systemin depends on a pair of distinct LRR-RKs termed SYR1 and SYR2. SYR1 acts as a genuine systemin receptor that binds systemin with high affinity and specificity. Further, we show that presence of SYR1, although not decisive for local and systemic wound responses, is important for defence against insect herbivory.