Pathways of electron transfer in Escherichia coli DNA photolyase: Trp306 to FADH.
Pathways of electron transfer in Escherichia coli DNA photolyase: Trp306 to FADH.
复制标题
大肠杆菌 DNA 光裂合酶中的电子转移途径:Trp306 至 FADH。
DOI:
10.1016/s0006-3495(99)77287-5
复制
发表时间:
1999
影响因子:
3.4
通讯作者:
Heelis,PF
中科院分区:
文献类型:
--
作者:
Cheung,MS;Daizadeh,I;Stuchebrukhov,AA;Heelis,PF
We describe the results of a series of theoretical calculations of electron transfer pathways between Trp306and *FADH·in theEscherichia coliDNA photolyase molecule, using the method of interatomic tunneling currents. It is found that there are two conformationally orthogonal tryptophans, Trp359and Trp382, between donor and acceptor that play a crucial role in the pathways of the electron transfer process. The pathways depend vitally on the aromaticity of tryptophans and the flavin molecule. The results of this calculation suggest that the major pathway of the electron transfer is due to a set of overlapping orthogonalπ-rings, which starts from the donor Trp306, runs through Trp359and Trp382, and finally reaches the flavin group of the acceptor complex, FADH.
登录
查看更多内容
影响因子:
56.9
作者:
PARK, HW;KIM, ST;DEISENHOFER, J
通讯作者:
DEISENHOFER, J
影响因子:
5.6
作者:
Bower, MJ;Cohen, FE;Dunbrack, RL
通讯作者:
Dunbrack, RL
影响因子:
2.9
作者:
LI, YF;HEELIS, PF;SANCAR, A
通讯作者:
SANCAR, A
DOI:
10.1073/pnas.94.8.3703
发表时间:
1997-04-15
影响因子:
11.1
作者:
Daizadeh, I;Medvedev, ES;Stuchebrukhov, AA
通讯作者:
Stuchebrukhov, AA
影响因子:
2.9
作者:
Sancar,GB;Smith,FW;Sancar,A
通讯作者:
Sancar,A