Brain activation in adults who stutter under delayed auditory feedback: An fMRI study
Brain activation in adults who stutter under delayed auditory feedback: An fMRI study
复制标题
延迟听觉反馈下口吃的成年人的大脑激活：一项功能磁共振成像研究
DOI：
10.1080/17549500802588161
复制
发表时间：
2009
影响因子：
1.8
通讯作者：
K. Mori
中科院分区：
文献类型：
--
作者：
Naomi Sakai;S. Masuda;T. Shimotomai;K. Mori
众所周知，有些口吃者在接受延迟听觉反馈（delayed auditory feedback，EFL）的情况下说话时，口吃症状会立即减轻。在本研究中，调查皮层激活语音生产过程中通过口吃效应，我们进行了功能磁共振成像（fMRI）实验下NAF（非改变反馈）和口吃条件下PWS和人谁不口吃（PWNS）。结果表明：（1）PWS在右侧额下回激活程度较高（2）PWNS组和PWS组右侧颞中回和右侧上级回的激活率均高于NAF组;（3）无论是NAF条件下，还是NRF条件下，PWNS均显示右侧辅助运动区和上级颞回的激活高于PWS;（4）PWNS在脑电刺激条件下，右侧额下回（BA 45）和双侧额下回（BA 46）的激活高于NAF。这些结果再次证实了大多数以前的研究结果与一些略有不同的激活区，并强调参与额下回和上级颞回流畅性障碍。
It is well known that some people who stutter (PWS) show an immediate reduction of stuttering when they speak under a condition of delayed auditory feedback (DAF). In the present study, to investigate cortical activations during speech production through the DAF effect, we performed functional magnetic resonance imaging (fMRI) experiments under the NAF (non-altered feedback) and DAF conditions for PWS and people who do not stutter (PWNS). The results are that (1) the PWS showed the higher activation in the right inferior frontal gyrus (Brodmann Area (BA)45) than the PWNS under the NAF condition; (2) the activations of the right superior temporal gyrus and the right middle temporal gyrus were higher under the DAF condition than the NAF in both PWNS and PWS groups; (3) the PWNS showed the higher activation in the right supplementary motor area and superior temporal gyrus than the PWS under both NAF and DAF conditions; (4) the PWNS showed the higher activation in the inferior frontal gyrus(the right BA45 and the bilateral BA46) under the DAF condition than the NAF. These results reconfirm most of the previous findings with some slightly different activation areas, and underscore the involvement of inferior frontal gyrus and superior temporal gyrus in dysfluency.