A GENE ESSENTIAL FOR THE SITE-SPECIFIC EXCISION OF ACTINOPHAGE R4 PROPHAGE GENOME FROM THE CHROMOSOME OF A LYSOGEN
A GENE ESSENTIAL FOR THE SITE-SPECIFIC EXCISION OF ACTINOPHAGE R4 PROPHAGE GENOME FROM THE CHROMOSOME OF A LYSOGEN
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从溶原性染色体上定点切除放线菌 R4 原噬菌体基因组所必需的基因
DOI：
10.2323/jgam.41.53
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发表时间：
1995
影响因子：
1.2
通讯作者：
M. Shirai
中科院分区：
文献类型：
--
作者：
M. Matsuura;T. Noguchi;T. Aida;M. Asayama;Hideo Takahashi;M. Shirai
在放线菌噬菌体R4的attP核心位点附近发现一个开放阅读框架（ORF 469），编码一个469个氨基酸的多肽。基因破坏实验表明，ORF469基因是从其宿主染色体上位点特异性切除原噬菌体R4基因组所必需的。该蛋白的氨基酸序列与枯草芽孢杆菌Tn2501和SpoIVCA的解离酶相似。
An open reading frame (ORF469) was found near the attP core site of the actinophage R4 which encoded a 469-amino acid polypeptide. A gene disruption experiment suggested that the ORF469 gene was essential for site-specific excision of the prophage R4 genome from its host chromosome. The predicted amino acid sequence of the protein showed a similarity to a resolvase of Tn2501 and SpoIVCA of Bacillus subtilis.
影响因子：
4.3
作者：
H. Sambrook
通讯作者：
H. Sambrook