Participation in research studies: Factors associated with failing to meet minority recruitment goals
Participation in research studies: Factors associated with failing to meet minority recruitment goals
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DOI：
10.1016/j.annepidem.2007.02.003
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发表时间：
2007-08-01
影响因子：
5.6
通讯作者：
Corbie-Smith, Giselle M.
中科院分区：
文献类型：
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作者：
Durant, Raegan W.;Davis, Roger B.;Corbie-Smith, Giselle M.
目得：为了确定招募的目标，调查人员为种族/少数民族和相关的因素，未能达到这些goals.METHODS：440名主要研究者（PIS）进行临床研究资助的国家心脏，肺，血液研究所（NHLBI）在2001年完成了邮寄调查，提供他们的少数民族招募目标和招募数据，为他们最近的NHLBI资助的研究。92%的PIS为非洲裔美国人设定了目标，68%为西班牙裔美国人，55%为亚裔美国人，35%为夏威夷土著人/太平洋岛民，23%的PIS为美洲印第安人/阿拉斯加土著人设定了招聘目标。在那些制定少数族裔招聘目标的PIS中，非洲裔美国人的平均招聘目标为31%，西班牙裔为16%，亚裔为9%。27%的PIS未能达到他们对非裔美国人的招聘目标，23%的亚裔美国人和23%的西班牙裔美国人。在调整多个研究者和试验特征后，研究类型（观察性与III期试验的比值比[OR] 1.8; 95%置信区间[CI] 1.2，3.4）完成研究入组（OR 2.0; 95% CI 1.2，3.4），PI识别出更多参与的主要障碍（OR 1.8; 95% CI 1.1，3.0）均与未能达到非洲裔美国人的招募目标相关。然而，没有任何因素始终与未能满足招聘目标在不同的种族/ethnic groups.CONCLUSIONS：调查人员往往不设置招聘目标的一些种族/ethnic groups。在征聘不同少数群体时，与未能实现征聘目标有关的因素各不相同。
PURPOSE: To determine the recruitment goals that investigators set for racial/ethnic minorities and the factors associated with failure to meet those goals.METHODS: Four hundred forty principal investigators (PIS) conducting clinical research funded by the National Heart, Lung, and Blood Institute (NHLBI) in 2001 completed a mailed survey providing their minority recruitment goals and enrollment data for their most recent NHLBI-funded study.RESULTS: Ninety-two percent of PIS set goals for African Americans, 68% for Hispanics, 55% for Asian Americans, 35% for Native Hawaiians/Pacific Islanders, and 23% of PIS set recruitment goals for American Indians/Native Alaskans. Among those PIS who did set minority recruitment goals, the mean goal for the recruitment of African Americans was 31%, 16% for Hispanics, and 9% for Asian Americans. Twenty-seven percent of PIS failed to meet their recruitment goals for African Americans, 23% for Asian Americans, and 23% for Hispanics. After adjusting for multiple investigator and trial characteristics, the type of study (odds ratio [OR] 1.8; 95% confidence interval [CI] 1.2, 3.4 for observational vs. phase III trial) completion of study enrollment (OR 2.0; 95% CI 1.2, 3.4), and PI identification of a larger number of major barriers to participation (OR 1.8; 95% CI 1.1, 3.0) were all associated with failure to meet recruitment goals for African Americans. However, no factors were consistently associated with failure to meet recruitment goals across different racial/ethnic groups.CONCLUSIONS: Investigators often do not set recruitment goals for some racial/ethnic groups. Factors associated with failure to meet recruitment goals vary in the recruitment of different minority groups.