Three novel terpenoids from Schisandra pubescens var. pubinervis
Three novel terpenoids from Schisandra pubescens var. pubinervis
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DOI：
10.1002/hlca.200690114
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发表时间：
2006-01-01
影响因子：
1.8
通讯作者：
Sun, Han-Dong
中科院分区：
文献类型：
--
作者：
Huang, Sheng-Xiong;Yang, Jing;Sun, Han-Dong
从五味子（Schisandra pubescens var. pubinervis）的叶和茎中分离到了3个新的萜类化合物pubinernoids A-C（1-3）和6个已知的倍半萜类化合物。新化合物的结构是在广泛的光谱分析的基础上建立的，包括应用二维核磁共振光谱技术。提出了一种似是而非的倍半萜类化合物2的形成方法（方案2），从愈创木二醇(4)作为生物成因前体开始，它也存在于提取物中。
Three new terpenoids, pubinernoids A-C (1-3), together with six known sesquiterpenoids, were isolated from the leaves and stems of Schisandra pubescens var. pubinervis. The structures of the new compounds were established on the basis of extensive spectroscopic analyses, including application of 2D-NMR spectroscopic techniques. A plausible formation of the sesquiterpenoid 2 is proposed (Scheme 2), starting from guaianediol (4) as the biogenetic precursor, which was also present in the extract.