A REDESCRIPTION OF ENTAMOEBA-HISTOLYTICA SCHAUDINN, 1903 (EMENDED WALKER, 1911) SEPARATING IT FROM ENTAMOEBA-DISPAR BRUMPT, 1925
A REDESCRIPTION OF ENTAMOEBA-HISTOLYTICA SCHAUDINN, 1903 (EMENDED WALKER, 1911) SEPARATING IT FROM ENTAMOEBA-DISPAR BRUMPT, 1925
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DOI：
10.1111/j.1550-7408.1993.tb04926.x
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发表时间：
1993-05-01
影响因子：
2.2
通讯作者：
CLARK, CG
中科院分区：
文献类型：
--
作者：
DIAMOND, LS;CLARK, CG
如何解释人类感染溶组织内阿米巴后侵袭性疾病的低发病率（10%）一直是临床和非临床研究者关注的焦点。一种可能的解释是存在两种形态相同的物种一种是入侵性病原体，另一种是非入侵性的。这是由Brumpt在1925年首次提出的，但他的解释几乎被忽视，直到1978年，当几个出版物中的第一个出现时，表明E。溶组织菌确实由两个物种组成。我们已经重新审查了Brumpt的说法，根据最近的生物化学，免疫学和遗传学研究，并得出结论，从这些调查中得出的数据提供了明确的证据支持他的假设。考虑到这一点，我们重新描述了侵入性寄生虫，保留名称溶组织内阿米巴Schaudinn，1903（Edended步行者，1911），并将其与Brumpt，Entamoeba dispar Brumpt，1925描述的非侵入性寄生虫区分开来。
Explaining the low incidence of invasive disease (10%) in humans infected with Entamoeba histolytica has occupied the attention of generations of both clinical and nonclinical investigators. One possible explanation would be the existence of two morphologically identical species-one an invasive pathogen, the other noninvasive. This was first proposed by Brumpt in 1925, but his explanation was virtually ignored until 1978 when the first of several publications appeared suggesting that E. histolytica did indeed consist of two species. We have reexamined Brumpt's claim in light of recent biochemical, immunological and genetic studies and conclude that the data derived from these investigations provide unequivocal evidence supporting his hypothesis. With this in mind, we redescribe the invasive parasite retaining the name Entamoeba histolytica Schaudinn, 1903 (Emended Walker, 1911), and set it apart from the noninvasive parasite described by Brumpt, Entamoeba dispar Brumpt, 1925.