Chronic (neuropathic) corneal pain and blepharospasm: Five case reports

Chronic (neuropathic) corneal pain and blepharospasm: Five case reports
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DOI:
10.1016/j.pain.2011.06.006
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发表时间:
2011-10-01
期刊:
影响因子:
7.4
通讯作者:
Rosenthal, Perry
Rosenthal, Perry
中科院分区:
医学1区
文献类型:
--
作者:
Borsook, David;Rosenthal, Perry

文献摘要

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疼痛和局限性肌张力障碍与慢性疼痛状况有关,如复杂的区域疼痛综合征。角膜疼痛,通常被称为“干眼”,可能是一种伴有神经丛异常的神经病理性疼痛状况。在此,我们介绍了5例明确的角膜疼痛患者(有相关的神经病理特征),以及神经丛变化和相关眼睑痉挛的客观测量。疼痛和眼睑痉挛之间的假定关系表明,在这两种情况下,基底神经节都有潜在的参与。(C)2011年,由Elsevier B.V.代表国际疼痛研究协会发表。
Pain and focal dystonias have been associated with chronic pain conditions such as complex regional pain syndrome. Corneal pain, frequently known as "dry eye'', may be a neuropathic pain condition with abnormalities of the nerve plexus. Here we present 5 case histories of patients with defined corneal pain (with associated neuropathic features) and objective measures of changes in the nerve plexus and associated blepharospasm. A putative relationship between pain and blepharospasm suggests potential involvement of the basal ganglia in both these conditions. (C) 2011 Published by Elsevier B. V. on behalf of International Association for the Study of Pain.