The role of infection and comorbidity: Factors that influence disparities in sepsis
The role of infection and comorbidity: Factors that influence disparities in sepsis
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DOI：
10.1097/01.ccm.0000239114.50519.0e
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发表时间：
2006-10-01
影响因子：
8.8
通讯作者：
Martin, Greg S.
中科院分区：
文献类型：
--
作者：
Esper, Annette M.;Moss, Marc;Martin, Greg S.
目标。在种族和性别的基础上，脓毒症的发病率存在很大的医疗差异。我们试图确定可能影响这些医疗差异发生的因素，包括感染来源、致病微生物和慢性合并症。设计：历史队列研究。研究背景：1979年至2003年美国急症护理医院。患者：根据《国际疾病统计分类第九次修订版》（ICD-9CM）的编码，从全国出院调查中确定诊断为败血症的住院患者。慢性合并症以及感染的来源和类型通过相应的ICD-9CM诊断进行表征。,没有。测量和主要结果。脓毒症的发病率是2000年美国人口普查年龄调整后的平均每10万例。男性和非白种人患败血症的风险增加。男性脓毒症的比例源分布和发病率均倾向于呼吸道源(36% vs. 29%, p
Objective. Large healthcare disparities exist in the incidence of sepsis based on both race and gender. We sought to determine factors that may influence the occurrence of these healthcare disparities, with respect to the source of infection, causal organisms, and chronic comorbid medical conditions.Design: Historical cohort study.Setting: U.S. acute care hospitals from 1979 to 2003.Patients: Hospitalized patients with a diagnosis of sepsis were identified from the National Hospital Discharge Survey per codes of the International Statistical Classification of Diseases, Ninth Revision (ICD-9CM). Chronic comorbid medical conditions and the source and type of infection were characterized by corresponding ICD-9CM diagnoses.Interventions., None.Measurements and Main Results. Sepsis incidence rates are mean cases per 100,000 after age adjustment to the 2000 U.S. Census. Males and nonwhite races were confirmed at increased risk for sepsis. Both proportional source distribution and incidence rates favored respiratory sources of sepsis in males (36% vs. 29%, p