A Cross-Sectional Study of HPV Vaccine Acceptability in Gaborone, Botswana
A Cross-Sectional Study of HPV Vaccine Acceptability in Gaborone, Botswana
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DOI：
10.1371/journal.pone.0025481
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发表时间：
2011-10-25
期刊：
影响因子：
3.7
通讯作者：
Brewer, Noel T.
中科院分区：
文献类型：
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作者：
DiAngi, Yumi Taylor;Panozzo, Catherine A.;Brewer, Noel T.
背景：宫颈癌是博茨瓦纳和撒哈拉以南非洲其他地区女性最常见的癌症。我们试图调查博茨瓦纳的父母是否可以接受 HPV 疫苗，博茨瓦纳最近批准了该疫苗用于预防宫颈癌。 方法和结果：我们在 2009 年（疫苗首次获得许可前后）进行了一项横断面调查，在博茨瓦纳首都哈博罗内的普通医学和艾滋病毒诊所招募了成年人。尽管只有9%（32/376）的受访者在调查前听说过HPV疫苗，但88%（329/376）的受访者表示他们肯定会让处于青春期的女儿接种HPV疫苗。大多数受访者会在公共或社区诊所（42％）或妇科或产科医生办公室（39％）为女儿接种疫苗，如果女儿的学校有疫苗，74％的人会为女儿接种疫苗。受访者更有可能表示，如果她们的教育程度较低（OR = 0.20，95% CI = 0.07-0.58）或居住地距离首都哈博罗内超过 30 公里（OR = 2.29，95% CI = 1.06-4.93），他们肯定会为女儿接种 HPV 疫苗。其他与可接受性相关的因素预计会参与接种 HPV 疫苗的决定，认为该疫苗很难获得，并且认为 HPV 相关疾病更加严重。结论：如果博茨瓦纳哈博罗内寻求医疗保健的父母的女儿能够广泛获得该疫苗，那么青春期女孩的 HPV 疫苗接种将是高度可接受的。潜在的 HPV 疫苗接种活动应提供有关 HPV 和疫苗的更多信息，并努力尽量减少障碍。
Background: Cervical cancer is the most common cancer among women in Botswana and elsewhere in Sub-Saharan Africa. We sought to examine whether HPV vaccine is acceptable among parents in Botswana, which recently licensed the vaccine to prevent cervical cancer.Methods and Findings: We conducted a cross-sectional survey in 2009, around the time the vaccine was first licensed, with adults recruited in general medicine and HIV clinics in Gaborone, the capital of Botswana. Although only 9% (32/376) of respondents had heard of HPV vaccine prior to the survey, 88% (329/376) said they definitely will have their adolescent daughters receive HPV vaccine. Most respondents would get the vaccine for their daughters at a public or community clinic (42%) or a gynecology or obstetrician's office (39%), and 74% would get it for a daughter if it were available at her school. Respondents were more likely to say that they definitely will get HPV vaccine for their daughters if they had less education (OR = 0.20, 95% CI = 0.07-0.58) or lived more than 30 kilometers from the capital, Gaborone (OR = 2.29, 95% CI = 1.06-4.93). Other correlates of acceptability were expecting to be involved in the decision to get HPV vaccine, thinking the vaccine would be hard to obtain, and perceiving greater severity of HPV-related diseases.Conclusions: HPV vaccination of adolescent girls would be highly acceptable if the vaccine became widely available to the daughters of healthcare seeking parents in Gaborone, Botswana. Potential HPV vaccination campaigns should provide more information about HPV and the vaccine as well as work to minimize barriers.