99mTc-HYNIC-TOC (99mTc-hydrazinonicotinyl-Tyr3-octreotide) scintigraphy identifying two separate causative tumors in a patient with tumor-induced osteomalacia (TIO).
99mTc-HYNIC-TOC (99mTc-hydrazinonicotinyl-Tyr3-octreotide) scintigraphy identifying two separate causative tumors in a patient with tumor-induced osteomalacia (TIO).
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DOI：
10.1097/rlu.0b013e3182996293
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发表时间：
2013-08
影响因子：
10.6
通讯作者：
H. Jing;Fang Li;Dingrong Zhong;H. Zhuang
中科院分区：
文献类型：
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作者：
H. Jing;Fang Li;Dingrong Zhong;H. Zhuang
导致骨软化症的肿瘤通常是良性的成纤维细胞生长因子-23，产生间叶性肿瘤，可以通过奥特鲁斯扫描发现。一名45岁的男子接受了(99m)Tc-HYNIC-TOC扫描，以发现可能导致骨软化症的罪魁祸首。图像显示左肱骨和右脚有异常活动。右足病变经病理证实为磷尿性间充质瘤。手术切除右脚肿瘤后，患者的症状迅速改善。然而，这种改善是暂时的，因为左肱骨有未切除的肿瘤。
Tumors that cause osteomalacia are generally benign fibroblast growth factor-23 producing mesenchymal tumors which can be detected by octreoscan. A 45-year-old man underwent (99m)Tc-HYNIC-TOC scan to detect a possible culprit causing osteomalacia. The images showed abnormal activity in the left humerus and in the right foot. The lesion of the right foot was confirmed pathologically as phosphaturic mesenchymal tumor. After surgical removal of the tumor in the right foot, the patient's symptoms were promptly improved. However, the improvement was transient due to the unresected tumor in the left humerus.