Cardiac Magnetic Resonance Assessment of Response to Cardiac Resynchronization Therapy and Programming Strategies.
Cardiac Magnetic Resonance Assessment of Response to Cardiac Resynchronization Therapy and Programming Strategies.
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DOI：
10.1016/j.jcmg.2021.06.015
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发表时间：
2021-12
期刊：
影响因子：
--
通讯作者：
Bilchick KC
中科院分区：
文献类型：
--
作者：
Gao X;Abdi M;Auger DA;Sun C;Hanson CA;Robinson AA;Schumann C;Oomen PJ;Ratcliffe S;Malhotra R;Darby A;Monfredi OJ;Mangrum JM;Mason P;Mazimba S;Holmes JW;Kramer CM;Epstein FH;Salerno M;Bilchick KC
带有心脏植入电子设备的 CMR 可以安全地提供高质量的右/左心室射血分数 (RVEF/LVEF) 评估和应变。目的是确定心脏再同步治疗 (CRT) 前后 CMR 电影和应变成像的可行性和有效性，以评估反应和最佳再同步起搏策略。在 CRT 之前和之后进行了电影成像 CMR、CURE-SVD 不同步参数的受激回波 (DENSE) 位移编码以及疤痕评估。虽然 CRT 前扫描构成了具有完整体积、应变和疤痕成像的单个“成像集”，但通过在成像集之间对扫描仪外部的设备重新编程，在 CRT 后扫描期间获得了具有完整应变和体积数据的多个成像集，用于双心室起搏 (BIVP)、左心室起搏 (LVP) 和异步心房起搏模式。对 50 名患者（中位年龄 70 岁 [IQR 50 至 86 岁]；48% 女性）进行了 100 次 CMR，总共 162 个成像集。与 CRT 起搏无关的 LV 舒张末期容量减少 (p=0.002) 比 RV 舒张末期容量相应减少 (p=0.16) 更为显着。最佳 CRT 起搏模式（BIVP 与 LVP）明显依赖于 PR 间期 (p=0.0006)。 PR 间期≥ 240 ms 时，BIVP 的 LVEF 和 RVEF 改善程度高于 LVP（分别为 p=0.025 和 p=0.002）；最佳模式（BIVP 与 LVP）随 PR 间隔 < 240 ms 变化。 CRT 前 DENSE CURE-SVD 较低与 CRT CURE-SVD 后 (r=-0.69；p<0.001)、LVESV (r=-0.58；p<0.001) 和 LVEF (r=-0.52；p<0.001) 的更大改善相关。 CMR 评估在 CRT 后单次扫描期间评估多种起搏模式是可行的，并为患者护理提供有关反应和最佳起搏策略的有用信息。
CMR with cardiac implantable electronic devices can safely provide high-quality right/left ventricular ejection fraction (RVEF/LVEF) assessments and strain. The objective was to determine the feasibility and effectiveness of CMR cine and strain imaging before and after cardiac resynchronization therapy (CRT) for assessment of response and the optimal resynchronization pacing strategy. CMR with cine imaging, displacement encoding with stimulated echoes (DENSE) for the CURE-SVD dyssynchrony parameter, and scar assessment was performed before and after CRT. While the pre-CRT scan constituted a single “imaging set” with complete volumetric, strain, and scar imaging, multiple imaging sets with complete strain and volumetric data were obtained during the post-CRT scan for biventricular pacing (BIVP), left ventricular pacing (LVP), and asynchronous atrial pacing modes by reprogramming the device outside the scanner between imaging sets. 100 CMRs with a total of 162 imaging sets were performed in 50 patients (median age 70 years [IQR 50 to 86 years]; 48% female). Reduction of LV end-diastolic volumes (p=0.002) independent of CRT pacing was more prominent than corresponding reductions in RV end-diastolic volumes (p=0.16). A clear dependence of the optimal CRT pacing mode (BIVP vs LVP) on the PR interval (p=0.0006) was demonstrated. The LVEF and RVEF improved more with BIVP than LVP with PR intervals ≥ 240 ms (p=0.025 and p=0.002, respectively); the optimal mode (BIVP v. LVP) was variable with PR intervals < 240 ms. A lower pre-CRT DENSE CURE-SVD was associated with greater improvements in the post-CRT CURE-SVD (r=−0.69; p<0.001), LVESV (r=−0.58; p<0.001), and LVEF (r=−0.52; p<0.001). CMR evaluation with assessment of multiple pacing modes during a single scan after CRT is feasible and provides useful information for patient care with respect to response and the optimal pacing strategy.
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DOI：
10.1111/j.1467-9868.2011.00771.x
发表时间：
2011-01-01
影响因子：
5.8
作者：
Tibshirani, Robert
通讯作者：
Tibshirani, Robert
DOI：
10.1016/j.echo.2007.05.001
发表时间：
2007-12-01
影响因子：
6.5
作者：
Takeuchi, Masaaki;Jacobs, Avrurn;Lang, Roberto M.
通讯作者：
Lang, Roberto M.
影响因子：
10.9
作者：
Spottiswoode BS;Zhong X;Lorenz CH;Mayosi BM;Meintjes EM;Epstein FH
通讯作者：
Epstein FH
影响因子：
158.5
作者：
Moss, Arthur J.;Hall, W. Jackson;Zareba, Wojciech
通讯作者：
Zareba, Wojciech
影响因子：
37.8
作者：
Chung, Eugene S.;Leon, Angel R.;Murillo, Jaime
通讯作者：
Murillo, Jaime