DF3 (CA15-3) antibody as a marker of cutaneous adnexal tumors.
DF3 (CA15-3) antibody as a marker of cutaneous adnexal tumors.
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DF3 (CA15-3) 抗体作为皮肤附件肿瘤的标志物。
DOI：
10.2340/000155557498100
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发表时间：
1994
影响因子：
3.6
通讯作者：
K. Ohara
中科院分区：
文献类型：
--
作者：
S. Yasui;I. Ando;A. Kukita;H. Hino;K. Ohara
DF 3（CA 15 -3）单克隆抗体检测上皮粘蛋白的20个氨基酸序列。在正常皮肤组织中，DF 3抗体与外泌和顶泌汗腺的皮脂腺和分泌区段表现出强且恒定的阳性反应性。所有表皮肿瘤均为DF 3阴性但低分化鳞状细胞癌。各种附属器肿瘤如小汗腺囊瘤、管状顶泌腺瘤、乳头状囊腺瘤、小汗腺汗孔瘤、小汗腺螺旋腺瘤、透明细胞汗腺瘤、混合细胞瘤、小汗腺汗孔癌、乳房外佩吉特病和腺样囊性癌是DF 3阳性的，这表明这些肿瘤产生上皮粘蛋白。
DF3(CA15-3) monoclonal antibody detects the 20 amino acid sequence of epithelial mucin. In normal cutaneous tissue DF3 antibody exhibits strong and constant positive reactivity with sebaceous and secretory segments of eccrine and apocrine sweat glands. All epidermal tumors are DF3 negative but poorly differentiated squamous cell carcinoma. Various adnexal tumors such as eccrine hidrocystoma, tubular apocrine adenoma, syringocystadenoma papilliferum, eccrine poroma, eccrine spiradenoma, clear cell hidradenoma, mixed cell tumor, eccrine porocarcinoma, extramammary Paget's disease and adenoid cystic carcinoma are DF3 positive, which indicates epithelial mucin production by these tumors.