Computational Architecture of the Parieto-Frontal Network Underlying Cognitive-Motor Control in Monkeys.
Computational Architecture of the Parieto-Frontal Network Underlying Cognitive-Motor Control in Monkeys.
复制标题
猴子认知运动控制的顶额网络的计算架构。
DOI：
10.1523/eneuro.0306-16.2017
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发表时间：
2017-01
期刊：
影响因子：
3.4
通讯作者：
Luppino G
中科院分区：
文献类型：
--
作者：
Caminiti R;Borra E;Visco-Comandini F;Battaglia-Mayer A;Averbeck BB;Luppino G
通过层次聚类分析研究了猴子内在顶叶和顶额叶连接的统计结构。根据他们的输入，顶叶和额叶区域被分为不同的簇，包括数量可变的区域，这些区域在大多数情况下占据连续的建筑领域。本地连接往往更强：即在同一集群的区域内。远处的额叶和顶叶区域是通过连接来瞄准的，这些连接在大多数情况下是相互的，而且往往强度不同。这些连接将由共享基本功能特性的区域形成的顶叶和额叶簇连接起来。这导致五个不同的中侧向支柱域跨越顶额叶系统的整个范围，即后顶叶、前顶叶、扣带皮层、额叶和前额叶皮层。由于域间连接，可以识别不同的信息处理流。这些流编码快速伸手及其控制、复杂的视觉运动动作空间、手部抓握、动作/意图识别、动眼意图和视觉注意、行为目标和策略以及奖励和决策价值结果。大多数这些流汇聚到系统的主要枢纽——扣带域。所有这些都嵌入在一个更大的眼手协调网络中，可以根据任务需求有选择地启动它们。
The statistical structure of intrinsic parietal and parieto-frontal connectivity in monkeys was studied through hierarchical cluster analysis. Based on their inputs, parietal and frontal areas were grouped into different clusters, including a variable number of areas that in most instances occupied contiguous architectonic fields. Connectivity tended to be stronger locally: that is, within areas of the same cluster. Distant frontal and parietal areas were targeted through connections that in most instances were reciprocal and often of different strength. These connections linked parietal and frontal clusters formed by areas sharing basic functional properties. This led to five different medio-laterally oriented pillar domains spanning the entire extent of the parieto-frontal system, in the posterior parietal, anterior parietal, cingulate, frontal, and prefrontal cortex. Different information processing streams could be identified thanks to inter-domain connectivity. These streams encode fast hand reaching and its control, complex visuomotor action spaces, hand grasping, action/intention recognition, oculomotor intention and visual attention, behavioral goals and strategies, and reward and decision value outcome. Most of these streams converge on the cingulate domain, the main hub of the system. All of them are embedded within a larger eye–hand coordination network, from which they can be selectively set in motion by task demands.