Ultrasound imaging of the murine kidney.

Ultrasound imaging of the murine kidney.
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DOI:
10.1007/978-1-61779-851-1_35
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发表时间:
2012-01-01
期刊:
Methods in molecular biology (Clifton, N.J.)
影响因子:
--
通讯作者:
McHugh, Kirk M
McHugh, Kirk M
中科院分区:
其他
文献类型:
--
作者:
Carpenter, Ashley R;Becknell, Brian;McHugh, Kirk M

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超声(US)是肾脏临床成像中最常见和侵入性最小的方式。超声在肾脏学中的一个重要应用是检测和监测肾脏的结构变化。美国技术的最新进展促进了类似技术在人类疾病动物模型中的应用。我们已经开发了一种简单的基于US的方法检测和定量的先天性梗阻性肾病小鼠模型,巨梯形(megabladder)小鼠肾积水。
Ultrasound (US) is the most common and least invasive modality for clinical imaging of the kidney. One important application of US in nephrology is the detection and monitoring of structural changes in the kidney. Recent advances in US technology have facilitated the application of similar techniques to animal models of human disease. We have developed a simple US-based method of detection and quantitation of hydronephrosis in a mouse model of congenital obstructive nephropathy, the megabladder (mgb) mouse.