Complex Task Performance Assessment (CTPA) and Functional Cognition in People With Parkinson's Disease

Complex Task Performance Assessment (CTPA) and Functional Cognition in People With Parkinson's Disease
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DOI:
10.5014/ajot.2019.031492
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发表时间:
2019-09-01
影响因子:
2.9
通讯作者:
Foster, Erin R.
Foster, Erin R.
中科院分区:
医学4区
文献类型:
--
作者:
Davis, Alison;Wolf, Timothy J.;Foster, Erin R.

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OBJECTIVE.本研究的目的是确定帕金森病(PD)如何影响功能性认知的复杂任务性能评估(CTPA)的评估,并检查CTPA性能与其他指标的执行功能的PD患者的关联。方法。无痴呆的PD志愿者(n = 20)和社区对照参与者(n = 19)完成了神经心理学测试、患者报告的结局指标和CTPA. CTTS。CTPA性能准确性无组间差异;然而,PD组完成CTPA所需时间长于对照组。在PD组中,低效的CTPA表现与较差的认知灵活性和较差的日常轮班和任务监测报告相关。执行功能下降,即认知灵活性和注意力控制,可能会损害PD患者的功能性认知。未来的研究更大,更多样化的样本是必要的,以确定判别效度和敏感性的CTPA。使用基于表现的评估,如CTPA,可以增加对PD患者功能认知的理解。
OBJECTIVE. The objective of this study was to determine how Parkinson's disease (PD) affects functional cognition as assessed by the Complex Task Performance Assessment (CTPA) and to examine the associations of CTPA performance with other indicators of executive function in people with PD.METHOD. Volunteers with PD without dementia (n = 20) and community control participants (n = 19) completed neuropsychological testing, patient-reported outcome measures, and the CTPA.RESULTS. There were no group differences for CTPA performance accuracy; however, the PD group took longer to complete the CTPA than did the control group. In the PD group, inefficient CTPA performance correlated with poorer cognitive flexibility and worse reported everyday shifting and task monitoring.CONCLUSION. Decreased executive function, namely cognitive flexibility and attentional control, may impair functional cognition in people with PD. Future studies with larger, more diverse samples are warranted to determine the discriminant validity and sensitivity of the CTPA. Use of performance-based assessments such as the CTPA may increase the understanding of functional cognition in people with PD.